Cardio Flashcards
Duration to wait until elective surgery for Angioplasty no stent
2 - 4 weeks
Duration to wait until elective surgery Bare metal Stent and CABG
6 weeks minimum 12 weeks prefered
Duration to wait until elective surgery Drug eluding stent
1 year
Duration to wait until elective surgery CABG
6 weeks minimum 12 weeks preferred
What’s the best treatment for stent thrombosis ?
Percutaneous coronary intervention. Best outcome achieve if blood flow restored in less than 90 min.
Compliance of ventricle is decreased by:
- Edad mas de 60 años 2. Ischemia 3. Pressure overload hypertrophy ( HTN or aortic stenosis) 4. Hypertrophic obstructive cardiomyopathy 5. Pericardial pressure
- Clinical take away here is that higher filling pressure are required to prime the ventricle
- Preservation of NSR and atrial kick are critically important to maintain priming function
- elevated filling pressures put patients at higher risk of pulmonary edema
- for any condition that reduces ventricular compliance , the CVP and PAOP may overstimate LVEDV

Compliance of ventricle is increased by:
Conditions that dilate the heart: Chronic aortic insufficiency Dilated cardiomyopathy
What is the initial elevation, peak elevation of CKMB and when does it return to baseline?
Initial elevation is 3 - 12 hrs Peak elevation is 24 hrs Return ti base line 48 - 72 hrs
What is the initial elevation, peak elevation of Troponin-I and when does it return to baseline?
Initial elevation is 3-12 hrs Peak elevation is 24 hrs Return to base line 5-10 days
What is the initial elevation, peak elevation of Troponin T and when does it return to baseline?
Initial elevation is 3-12 hrs Peak elevation 12-48 hrs Return to base line is 5-14 days
What are the Risk factors for cardiovascular morbidity and Mortality?
- High risk surgery
- History of ischemic heart disease ( unstable angina confers the greatest risk of perioperative MI)
- History of CHF
- History of cerebrovascular disease
- Diabetes mellitus
- Serum Creatinine >2 md /dl (Normal 0.7-1.5mg/dl)
Define unstable angina
Unstable angina is definced as
- angina at rest
- new onset angina (<2 months)
- increasing symptoms ( intensity, frequency, duration) duration exceeds 30 minutes
- symptoms have become less responsive to medical therapy.
Risk of having perioperative MI in Patients with previous MI
When is the greatest highest risk of reinfartion?
- General Population= 0.3%
- MI >6 moths = 6%
- MI 3-6 months= 15%
- MI<3 months= 30 %
The highest risk of reinfartion is greatest within 30 days of an acute MI
What is the ACC/AHA guideline for recent MI?
The ACC/AHA guidelines recommend a minimum of 4 - 6 weeks bedore considering elective surgery in a patient with a recent MI.
What are the cardiovascular risk for surgical procedures?
- High Risk (>5%)
- Emergency surgery ( more in elderly)
- Open aortic surgery
- Peripheral vascular surgery
- Long surgical procedure with significant volume shift and /or blood loss.
- Intermediate risk(1-5%)
- Carotid endarterectomy
- Head and neck surgery
- Intrathorasic or intraperitoneal surgery
- Orthopedic surgery
- Prostate surgery
- Low Risk(<1%)
- Endoscopic procedure
- cataract surgery
- superficial procedure
- Breast surgery
- ambulatory procedure
What’s the modified NY association functional classification of Heart Failure?
- Class I: Assyntomatic
- ClassII: Symptomatic with moderate activity
- Class III: Symptomatic with mild activity
- Class IV: symptomatic at rest
What Factors that reduce Oxygen Delivery or Supply ?
- Decreases CPP
- Tachycardia
- increased EDP
- decreassed AoDP
- decreased vessel diameter
- Decreased CaO2
- Hypoxemia
- Anemia
- Decreased Oxygen extracion
- deceased P50
- Decreased capillary Desnsity
What factors increase O2 demand?
- Tachycardia
- hypertension
- increase wall tension
- increase EDV
- Increased afterload
- SNS stimulation
- Increased contractility
What is the best lead to monitor intraoperative ST changes?
- Normal EKG or no EKG on file : V3 > V4 > V5 > III > AVF
- Abnormal EKG: monitor region at freatest risk of ischemia
In patient with CAD
- 5 cable EKG: V3, AVF and MCL5 or III
- 3 cable EKG: AVF and MCL5
Lead II is best for monitoring for dyssrhythmiaswith a narrow QRS where P wave analysis is critical for DX ( junctional, a-fib or a-flutter)
In how many hours doesmust posoperative miocaldial infartion occurs?
within 48 hrs after surgery
How to treat myocardial ischemia?
- Increased O2 demand
- increased HR- use beta blocker to HR <80
- increased BP- increase depth of anesthesia or use a vasodilator
- Increased PAOP- nitroglycerine
- Decreased O2 Demand
- decreases HR- Anticholinergic, pacing
- decreased BP- vasoconstrictor, decreased depth of anesthesia
- increased PAOP- Nitroglycerine, inotrope
What’s the hallmark of Systolic heart failure?
What causes Systolic Heart Failure?
in systolic heart failure the ventricle doesn’t empty well
The hallmark is
- decreased ejection fraction
- increased end-diastolic volume ( volume overload commonly caused systolic disfuction)
- since heart can’t squeeze well a greater volume will stay in the ventricle after each contraction
- less oxygen rich blood is delivered to the periphery
- the arterial-venous oxygen content difference is increased
- Compensatory mechanism: Increases SNS, increases RAAS, increases Preload
Is caused by:
- Myocardial ISchemia
- Valve insufficiency
- Dilated cadiomyopathy
- Eccentric
- Increased Compliance
What happens during diastolic failure ?
What are the characteristics?
What causes diastolic failure?
Diastolic failure occurs when the heart is unable to relax and accept an incoming volume because ventricular compliance is reduced.
Characteristics:
- symptomatic heart failure with a normal ejection fraction
Contractility is generally preserve until late stage of disease.
Causes:
- Myocardial Ischemia
- Valve stenosis
- Hypertension
- Hyperthophic cardiomaopathy
- Cor pulmonale
- Obesity
- increased compliance of ventricle
What is cardiac remodeling and what medication reversed it?
is the ability of the heart to change it’s size, shape and function in an attemps to preserve cardiac output.
Cardiac remodeling can be reverse by:
- ACE inhibitors (pril)
- Spironolactone







