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CVS Histology > Cardiac Muscle Fibers > Flashcards

Cardiac Muscle Fibers Flashcards

1
Q

Cardiac muscle is …… in origin

A

Mesodermal

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2
Q

Mention arrangement of cardiac muscle fibers

A

Longitudinal, tranverse & oblique

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3
Q

Myosin is present in ….., the connected end is attached to …..

A 
A band
Transverse filament (M line)
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4
Q

Actin is found in ….., its connected end is attached to …..

A

I & A bands

Z line

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5
Q

SR is composed of ….&….

Define them

A

Sarcotubules: anastomosing tubules surrounding myofibrils

Terminal cisternae: ring around myofibil close to T-tubule

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6
Q

Each sarcomere has …. T-tubule(s)

A

One

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7
Q

Define diad & its site

A

Level of Z-line

1 T-tubule + 1 terminal cisternae of SR

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8
Q

Intercalated disc is composed of ……&……

Describe their position

A

Tranverse portions: right angle to sarcolemma

Longitudinal portions: parallel to sarcolemma

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9
Q

Components of transverse portion and function

A

Fascia adherens, desmosomes (prevent separation), gap junction (allow direct communication & transmission of impulses)

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10
Q

Components of longitunidal portion

A

Large gap junctions

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11
Q

Electron dense secretory granules are found in …… . Contain …… which …..

A

Right atrium, to lesser extent left atrium & ventricles
Atrial natriuretic factor
Controlling blood pressure

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12
Q

Damage of mycardium heals by ….

A

Fibrosis

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13
Q

Describe composition of epicardium

A

Mesothelial cells

Subserous layer of loose connective tissue, contains coronary blood vessles, fat cells & nerves

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14
Q

Cardiac muscle fibers are found in ….

A

Myocardium

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15
Q

Describe composition of endocardium

A
  1. Endothelium (simple squamous epithelium & subendothelil CT)
  2. Thick middle layer of CT rich in elastic fibers
  3. Subendocardium: loose CT with blood vessels, nerves & Purkinje fibers.
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16
Q

Compare angina & myocardial infarction

A

A: slowly progressive reduction of coronary artery lumen by atheroma impairs oxygenation of ventricular muscle leading to chest pain usually brought by exertion.
M.I.: complete obstruction of one of the coronary arteries results in oxygen deprivation of an area of heart. Muscle fibers die.

17
Q

Middle layer of CT of valves is rich in …..

A

Elastic & collagen fibers

18
Q

Moderator band consists of ……

A

Purkinje fibers

19
Q

GR: Purkinje fibers are pale in colour.

A

Due to high content of glycogen

20
Q

Mention inclusions of cardiac muscle fibers

A

Glycogen, lipid droplets, lipofuscin

21
Q

Comapre SR & T-tubule of cardiac muscle fibers & skeletal muscle

A

SR is less developed but T tubule are wider and numerous than those of skeletal muscle.

CVS Histology (2 decks)

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