cardiac mucle Flashcards

1
Q

What are the characteristics of a cardiac muscle

A
  • branching cells
  • one/two nuclei per cell
  • straithed
  • Ca++ source: sarcoplasmic reticulum + extracellular liquid
  • contains actin and myosin
  • tropomyosin + troponin
  • abundant mitochondria
  • INVOLUNTARY
  • medium speed contractions
  • NO MOTOR UNITS
  • An extensive system of T-tubules (that release large quantities of calcium ions)
  • gap junctions
  • contains intercalated discs
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2
Q

What is the thee different type of muscle in cardiac muscle?

A
  • atrialmuscle
  • ventriacular muscle
  • specialazed exitatory and conductive muscle fibers
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3
Q

what are the 2 types of cells in cardiac muscle?

A
Autorhytmic cells (pacemaker) 1%
Contractive cells 99%
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4
Q

Whats is the characteristics of the aurorytmic cells in cardiac muscle?

A
  • pacemaker cells 1%
  • forms the conduction system of the heart
  • are distrube in orderly fashion SAN —> AVN –> BUNDLE OF HIS – Right and left BUNDLE BRANCHES —> PJURKINES FIBERS.
  • Autorytmic = spontaneous generate and discharge an electrician impulse within the heart
  • Exitability= cell responds to an electrical charge
  • Conductivity = ability to transmit an electricn impulse from ine cell to on other
  • Refractory- the inability of the cardiac cell to initiate another action potential for some duration of time (250ms)
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5
Q

Whats is the characteristics of the Contractile cells in cardiac muscle?

A
  • Makes muscular walls of the atrium and ventricles
  • contractility = the ability of the cell to contract in response to stimulation
  • Extensibility= the ability of the cell to stretch
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6
Q

What is an intercalated disc?

A

Gapjuctions = allows free diffusion of ions an action potential between adjacent fibers (electrical union)
- Desmosomes and fasciae adherens hold cells tightly together (mechanical union)

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7
Q

What is syncytium?

A
Heart = uniqe functional unite: functional syncytium.
ATRIAL SYNCYTIUM (2 walls of the atria)

VENTRICULAR SYNCYTIUM (walls of 2 ventricles)

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8
Q

What are the characteristics of the conducting system?

A
  • Sinoatrial node SAN
  • Atrioventricular node AVN
  • Bundle of his
  • R and L bundle branches
  • Pjurkines fibers
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9
Q

what is SA NODE

A

= acts like a pacemaker, have the fastest rate of the general action potential.

  • generates impulses automatically
  • specialized muscle cells
  • no neurons cells
  • triggers and organizes the heart beat
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10
Q

3 types of cardiac muscle?

A

atrial,
ventricular muscle
specialized excitatory and conductive muscle fiders

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11
Q

what is sarcoplasmic reticulum?

A

its a membrane-bound structure found within muscle cells that are similar to endopalsmatic reticulum. the main function is to store calciums

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12
Q

what are the characteristics of sarcoplasmic reticulum in cardiac muscle?

A

the terminal cisternae contains less Ca++ than skeletal muscle, the strength of the cardiac muscle depends largely on the influx of Ca++ from extracellular space in addition to tah released from the sarcoplasmic reticulum

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13
Q

what is an intercalated disk?

A

membrane junctions that hold adjacent cells together and transmit the concentration force to each cell

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14
Q

gap junctions?

A

are the most important intercellular junctions that allow interchange and communication between sarcoplasm o connected cardiac muscles

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15
Q

which are the two types of cells in the cardiac heart?

A

autorhytmic (pacemaker) 1%

contractile cells

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16
Q

characteristics of the sequence in cardiac muscle?

A

are distrube in orderly fashion SAN —> AVN –> BUNDLE OF HIS – Right and left BUNDLE BRANCHES —> PJURKINES FIBERS.

17
Q

which is the functional syncytium of the cardiac muscle

A

atrial synscytium and ventricular syncytium

18
Q

name the unions if the intercalated disks

A

gapjuctions that allow free diffussion of ions and AP between adjacent fivers (electrial union)

desmosomes and fasciae adherens (hold cells tighty togehter (menichal union)

19
Q

what are the function of desmosomes and fascia ahherens?

A

its a mechnical union) hold cells tigthly togehter

20
Q

atrial syncytium contists….

A

2 walls of the atria

21
Q

what is the electrical activity of the heart?

A

autorythmicity–> ability to spontanius generate and discharge an electrician impulse
exitability ..> the ability of the cell to resond to an electrical impulse
conductivity—> the ability to transmitt an elecrican impulse from ine cell to another
Refractory–> the inability of cardiac cells to iniatiate another action pontentiall fomr some durationof time (-250ms)

22
Q

describe the contractile cells in heart

A

make upp the walls of atrium an ventricles

  • possess specific properties:
  • contractility – the abillity for a celll to contract
  • extensibility – the ability of the cell to stretch
23
Q

describe the all or non response

A

either both atria contract, or both do not contract

either both ventricles contract or do not contract at all

24
Q

What rate do the SA node have?

A

70mph

25
Q

whats a non-SA node tissue?

A

a latent pacemaker than can take over if the normal pacemaker fails

26
Q

what are the electrical activity of cardiac muscle?

A

can generate impulses automatically
specialized muscle cells NOT NERVOUS CELLS
trigger and organize heart beat

27
Q

describe the electrical activity of The cardiac muscle

A

the are all excitable - able to respond to an external stimuli by generating an electrical response followed by corresponding contractile response

28
Q

what are the characteristics of action potential in contractile fibers

A

larger action potential - platue
fast Na+ channels and slow ca++
heart muscle membrane permeability to k diminshes 5 times