Cardiac - inflammation Flashcards
Endocardium
Inner most layer of the heart
Includes the heart valves
Myocardium
Thickest layer of the heart
Middle layer
Pericardium
Outer most layer of the heart and consists of two layers
What is ineffective endocarditis?
Infection of the innermost later of the heart (endocardium) and includes the heart valves
What is the pathology of endocarditis?
- Caused by blood turbulence in the heart which allows bacterial, fungal or viral organisms to infect valves or other endothelial surfaces
- Inflammation leads to vegetation formation as microbe stick to endothelial surfaces
- Infection spreads and damages the heart valves and supporting structure like the myocardium
What occurs when the heart valves are damaged?
Effects electrical conduction, leads to dysrhythmias and heart blocks
If endocarditis spreads to the myocardium what can happen?
heart failure
Vegetation on heart can cause…
It can cause an emboli in the blood stream because they are fragile and break off
The three categories of risk factors for endocarditis include?
- Cardiac
- Non-cardiac
- Procedural
Cardiac risk factors include? (6)
- Prior endocarditis
- Prosthetic heart valve
- valvular disease
- Rheumatic heart disease
- Congenital heart defects
- Pacemakers
How do cardiac issue put the patient at more risk for endocarditis?
Makes the heart more susceptible to pathogens
Basic procedure hold an additional risk due to this
Non-cardiac risk factors include?
- Hospital acquired infections
2. IV drug abuse
Procedural risk factors include?
- Intravascular devices
- Dental work
- Tonsillectomy
- Wound infections
What is recommended for those at high risk for endocarditis when underling a procedure?
prophylaxic antibiotics
Why is endocarditis hard to diagnose?
the s/s are non-specific and they don’t occur in all cases
What are the clinical manifestations of endocarditis? (8)
- Fever
- New heart murmur or worsening heart murmur
- Flu-like symptoms
- AV heart block
- Vascular manifestations due to microembolization of vegetation
- Heart failure often r/t LS valve dysfunction (s/s look like LSHF)
- Decrease CO –> decreased UO, SOB
- Further damage to valves
Vascular manifestation: Oslers nodes
blotchy red patches on hands from endocarditis - mainly on fingers
Vascular manifestation: Janeway’s lesions
Small round bruise like dots on bottom of feet
Is left-sided embolization common? what valves does it affect?
Yes it is common
Affects the aortic and mitral valves so enters arterial circulation and s/s are based on where the blood goes
Spleen left embolization s/s
- Sharp LUQ pain
- Splenomegaly
- Abdominal rigidity
- Local tenderness
Kidney left embolization s/s
- Flank pain
- Hematuria
- Renal failure
Limbs left embolization s/s
- Ischemia
- Limb infarction
- Gangrene
Brain left embolization s/s
- Hemiplegia
- Ataxia
- Aphasia
- Visual changes
- Altered LOC
Is right side embolization common?
No