ARDS Flashcards
RF is
a failure in gas exchange (oxygenation or ventilation)
ARDS is
direct or indirect lung injury from progressive hypoxemia, infiltration, and fibrosis of lung tissue
Hypoxemic RF is..
PaO2 less than 60 and normal PaCO2
Hypercapnia RF is..
respiratory acidosis, PacO2 is above 50, and pH less than 7.35
Risk factors for respiratory failure (10)
- Airway obstruction
- chest wall injury
- Opioid excess/OD
- VQ mismatch (COPD, atelectasis, PE, pneumothorax, ARDS, restrictive lung disease/fibrosis)
- Impaired diffusion (pulmonary edema, ARDS)
What are the hypercapnia clinical manifestations?
HA, confusion, decreased LOC, tachycardia, flushed skin
What are the hypoxemia clinical manifestations?
increased HR, RR, BP
What are the early signs of RF?
tachycardia increased BP dyspnea restlessness anxiety fatigue
What are the late signs for RF?
cyanosis
decreased BP
agonal respiration
coma
How do you diagnose RF?
ABG, chemistry, CBC, coats, chest x ray, chest CT, sputum culture, history and physical
What should the pulse ox be kept at for respiratory failure?
above 94
What is the hemoglobin threshold for transfusing RBCs?
7
What is a sudden and progressive form of RF? and how long is the onset?
ARDS
less than 7 days
What are the hallmark signs of ARDS?
- Refractory hypoxemia (hypoxemia that does not improve no matter if you increase the O2)
- Bilateral (must be in both lungs) opacities
- Widespread inflammation
What is ARDS?
diffuse alveolar capillary membrane damage from a direct or indirect injury
What is the most common cause of ARDS?
sepsis
What is a predisposing condition of ARDS?
SIRS: systemic inflammatory response, trauma, gut ischemia, lung injury, consequence of MODS
What is a mild, moderate and severe P/F ratio for ARDS?
Mild: less than 300
Moderate: less than 200
Severe: less than 100
ALL with PEEP or CPAP more than 5 cmH2O
What is the timing of ARDS?
one week of clinical insult or worsening respiratory symptoms
What are direct injury to the lungs that can lead to ARDS? (9)
- Aspiration
- Pneumonia
- Sepsis
- Gastric aspiration, chest trauma, embolism, inhalation injury, near drowning. O2 toxicity
What are indirect injury to the lungs that can lead to ARDS? (11)
- Sepsis: gram -
- Severe trauma
- Acute pancreatitis, cardiopulmonary bypass, shock, DIC, gut ischemia, OD, burns, TBI, TRALI