Cardiac function and its control Flashcards
4 phases of the pressure-volume curve
diastole isovolumetric contraction systole isovolumetric relaxation
Preload
The stretch on the myocyte fibres before they commencecontraction
normal SV
100ml
normal EDP
15mmHg
Exaplain the Frank Starling relationship
more stretch on the cardiac myocytes by increased venous return (increased EDV), results in more tension in the wall and increased SV
What can increase afterload
arterial hypertension LV outflow tract obstruction (eg. aortic stenosis)
Afterload
the load encountered by the ventricle as it commences contraction
for any volume of blood, the pressure depends on
the compliance of the wall the active tension in the wall
stroke volume can be increased by
increasing EDV (increased venous return) increasing ventricular contractility (inotropy)
normal ESP
5 mmHg
normal ESV
75ml
what increases preload
increased venous return