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autoantibodies > Cardiac drugs > Flashcards

Cardiac drugs Flashcards

1
Q

Spironolactone mechanism

A

Aldosterone antagonist acts in cortical collecting ducts

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2
Q

Bisoprolol mechanism

A

Competitively blocks B1 receptors

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3
Q

Propranolol mechanism

A

Blocks B1 + B2 receptors

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4
Q

Indapamide mechanism

A

Inhibits sodium reabsorption of DCT by blocking thiazide sensitive NaCl symporter

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5
Q

Warfarin mechanism

A

Inhibits epoxide reductase preventing Vit K activation - prevents carboxylation of 2, 7, 9, 10

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6
Q

Clopidogrel mechanism

A

P2Y12 ADP antagonist - inhibits platelet activation

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7
Q

Furosemide mechanism

A

Loop diuretic inhibits NaKCl co-transporter in thick ascending limb

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8
Q

Bumetanide mechanism

A

Loop diuretic inhibits NaKCl cotransporter in thick ascending limb

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9
Q

Amiloride mechanism

A

Potassium sparing diuretic blocks epithelial sodium channel in DCT

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10
Q

Metolazone mechanism

A

Thiazide like diuretic

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11
Q

Ticagrelor mechanism

A

ADP receptor antagonist PYY12

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12
Q

LMWH mechanism

A

Potentiates antithrombin III, inhibits factor Xa

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13
Q

Heparin mechanism

A

Potentiates antithrombin III, inhibits factor IXa, Xa, XIa, XIIa

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14
Q

Eplerenone mechanism

A

Aldosterone antagonist, potassium sparing diuretic

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15
Q

Amiodarone mechanism

A

Blocks potassium channels

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16
Q

Aspirin mechanism

A

Blocks cyclooxygenase 1 & 2, responsible for thromboxane A2 - platelet aggregation

17
Q

Prasugrel mechanism

A

ADP antagonist, P2Y12 antagonist

18
Q

Dabigatran mechanism

A

Direct thrombin inhibitor

19
Q

Atropine mechanism

A

Muscarinic acetylcholine antagonist

20
Q

Adenosine mechanism

A

Blocks the AV node

21
Q

Digoxin mechanism

A

Inhibits Na-K-ATPase pump

22
Q

Tirofiban mechanism

A

GpIIb/IIIa inhibitor

23
Q

Abciximab mechanism

A

GpIIb/IIIa inhibitor

24
Q

Bivalirudin mechanism

A

Reversible direct thrombin inhibitor

25
Q

Flecainide mechanism

A

Sodium channel blocker

autoantibodies (3 decks)

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