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autoantibodies > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

TPO

A

Hashimoto’s thyroiditis

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2
Q

TSH receptor

A

Grave’s disease

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3
Q

IgG anti-platelet

A

ITP

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4
Q

21-hydroxylase

A

Addison’s

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5
Q

Ro

A

SLE antibody associated with congenital heart block, Sjogren’s

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6
Q

GM1

A

AIDP

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7
Q

MuSK

A

Myasthenia gravis

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8
Q

NMDA

A

Encephalitis

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9
Q

Intrinsic factor

A

Pernicious anaemia

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10
Q

Gastric parietal cell

A

Pernicious anaemia

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11
Q

Jo-1

A

Polymyositis

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12
Q

CCP

A

Rheumatoid arthritis

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13
Q

Rheumatoid factor

A

Rheumatoid arthritis

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14
Q

Most specific Ab for rheumatoid arthritis

A

CCP

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15
Q

Cardiolipin

A

Antiphospholipid syndrome

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16
Q

Beta 2 glycoprotein

A

Antiphospholipid syndrome

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17
Q

Lupus anticoagulant

A

Antiphospholipid syndrome

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18
Q

SMA smooth muscle antibody

A

Autoimmune hepatitis type 1

19
Q

LKM1 liver kidney microsomal

A

Autoimmune hepatitis type 2

20
Q

QG1b

A

Miller Fisher syndrome

21
Q

Ganglioside

A

Guillian Barre syndrome

22
Q

Centromere

A

Limited cutaneous systemic sclerosis

23
Q

Scl-70

A

Diffuse cutaneous systemic sclerosis (bad prognostic factor)

24
Q

La

A

Sjogren’s

25
Q

Presynaptic voltage gated calcium channels

A

Lambert Eaton Myasthenic Syndrome

26
Q

GAD

A

Paraneoplastic stiff person syndrome (breast, colorectal, small cell lung cancer)

27
Q

Hu

A

Paraneoplastic sensory neuropathy + cerebellar syndrome + encephalomyelitis (SCLC, neuroblastomas)

28
Q

Purkinje cell

A

Paraneoplastic peripheral neuropathy (breast cancer)

29
Q

Yo

A

Cerebellar syndrome (ovarian, breast cancer)

30
Q

Ri

A

Opsoclonus myoclonus (breast, SCLC)

31
Q

DsDNA

A

SLE

32
Q

Sm (Smith)

A

SLE

33
Q

SLE most sensitive

A

ANA

34
Q

SLE most specific

A

DsDNA & Smith

35
Q

Histone

A

Drug induced lupus

36
Q

GBM glomerular basement membrane

A

Goodpasture’s

37
Q

Desmoglein 3

A

Pemphigus vulgaris

38
Q

Hemidesmosome

A

Pemphigoid

39
Q

cANCA

A

GPA, MPA

40
Q

pANCA - MPO

A

eGPA

41
Q

U1-RNP

A

Mixed connective tissue disease

42
Q

Phospholipase A2

A

Primary membranous glomerulonephritis

43
Q

Mi-2

A

Dermatomyositis

autoantibodies (3 decks)

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