Cardiac Cycle and Cardiac Output Flashcards

1
Q

repetitive sequence of events with each heart beat

A
  1. flow into atria, continuous except when they contract. inflow leads to pressure rise
  2. opening of AV valves - flow to ventricles
  3. atrial systole - completes filling of ventricles
  4. ventricular systole (atrial diastole) - pressure rise closes AV valves, opens aortic and pulmonary valves
  5. ventricular diastole - causes closure of aortic and pulmonary valves
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2
Q

1st heart sound

A

closing of AV valves

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3
Q

2nd heart sound

A

closing of semilunar valves

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4
Q

3rd heart sound

A

early diastole of young and trained athletes
normally absent after middle age
termes ventricular gallop
re-emergence in later life indicates abnormality

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5
Q

4th heart sound

A

caused by turbulent blood flow
due to stiffening of walls of left ventricle
occurs prior to 1st sound
atrial gallop

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6
Q

do the chambers of the heart empty completely

A

no

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7
Q

what helps maintain pressure in arterial system during diastole

A

elastic arterial tree

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8
Q

stroke volume

A

volume of blood pumped by each ventricle per beat
may double during exercise

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9
Q

ejection fraction

A

% volume pumped out
normally 55-60%
exercise 80%
heart failure 20%

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10
Q

systemic arterial pressure

A

remains high throughout cycle due to elasticity of vessel walls and peripheral resistance

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11
Q

cardiac output

A

volume of blood pumped per minute by each ventricle
CO = HR x SV

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12
Q

effect of HR on cardiac output

A

normally increased HR is associated with increased CO
if decreased filling time then decreased SV
** venous return determines cardiac output

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13
Q

what is stroke volume dependent on

A

contractility
end diastolic volume

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14
Q

contractility

A

the force of contraction
e.g. adrenaline increases force which increases SV

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15
Q

end diastolic volume

A

the volume of blood in ventricle at the end of diastole
force is stronger the more muscle fibres are stretched
frank-starling mechanism or starlings law of the hearr
SV ∝ diastolic filling

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16
Q

frank-starling mechanism

A

aka preload
important in:
- ensuring heart can deal with wide variations in venous return
- balancing the outputs of the two sides of the heart

17
Q

peripheral resistance (afterload)

A

resistance to blood flow away from the heart - altered by dilation or constriction of blood vessels (mainly pre-capillary resistance arteries)

CO = BP/PR