*Cardiac Arrest Flashcards

1
Q

Define cardiac arrest.

A

Sudden cardiac arrest is a sudden state of circulatory failure due to a loss of cardiac systolic function.

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2
Q

What are the 4 specific cardiac rhythm disturbances that can cause cardiac arrest?

A
  • Ventricular fibrillation,
  • Pulseless ventricular tachycardia (VT) - e.g. TDP
  • Pulseless electrical activity (PEA)
  • Asystole.
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3
Q

What are the reversible causes of cardiac arrest?

A

4Hs = hypoxia, hypothermia, hypovolaemia, hyperkalaemia(hypokalaemia, hypoglycaemia, hypocalcaemia/acidaemia)

4Ts = tension pneumothorax, tamponade, thrombosis(ACS/VTE), toxins

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4
Q

What is shown here?

A

*Torsades de pointes = a sub-group of polymorphic VT in patients with an underlying prolonged QT interval, sometimes related to hypomagnesaemia.

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5
Q

What are the two most common shockable rhythms?

A
  • Pulseless VT
  • VF
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6
Q

What is the survival rate for out of hospital cardiac arrest?

A

VF = <20%

cardiac arrest = <10%

In hospital this is 36% and 11% resepctively. This is 30 day survival rates.

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7
Q

What are the risk factors for cardiac arrest?

A
  • coronary artery disease (CAD)
  • left ventricular dysfunction
  • hypertrophic cardiomyopathy (HCM)
  • arrhythmogenic right ventricular dysplasia (ARVD)
  • long QT syndrome (LQTS)
  • medications that prolong the QT interval or cause electrolyte disturbances - quinidine, procainamide, sotalol, amiodarone, disopyramide, dofetilide, phenothiazines, and TCAs
  • acute medical or surgical emergency
  • illicit substances e.g. opioids

weak:

  • Brugada syndrome
  • valvular heart disease
  • smoking
  • history of eating disorders
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8
Q

What are the most common causes of cardiac arrest?

A

Ischaemic heart disease (62%)

Cardiomyopathy/dysrhythmias (9%)

Other cardiovascular disease (12%)

VF and VT may also be caused by:

  • R-on-T phenomenon
  • prolonged QT interval secondary to medicines
  • electrolyte abnormalities
  • familial syndromes of conduction abnormality
  • drug intoxication (e.g. cocaine)
  • cardiomyopathies
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9
Q

What are the most common causes of PEA?

A
  • MI
  • hypovolaemia
  • hypoxia
  • PE
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10
Q

What are the clinical signs of cardiac arrest?

A

Do ABCDE assessment

  • Unresponsive
  • No normal breathing
  • No signs of circulation

Assessment before or after successful resuscitation:

  • Symptoms
  • PMH
  • FH
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11
Q

What investigations should be done during/after cardiac arrest?

A
  • During - continuous cardiac monitoring
  • FBC - look for haemorrhage
  • Serum electrolytes - look for abnormality
  • ABG - acid-base status
  • Cardiac biomarkers - troponins
  • Echo - assess contractility, volume status, tamponade, LV function.

Other:

  • ECG - prolonged QT interval, ST-segment or T-wave changes (indicating ischaemia), conduction abnormalities, V hypertrophy, cardiomyopathy, ARVD.
  • coronary angiography +/- PCI
  • CXR - pneumothorax, pulmonary oedema, endotracheal tube placement.
  • toxicology screen - VT drugs
  • Cardiac MRI - assess for ARVD/cardiomyopathies.
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12
Q

What approaches are used by bystanders for cardiac arrest?

A

BLS - DRS ABC

  • 30 chest compressions 2 rescue breaths at 100/min with depth 5-6cm
  • Dial 999 and ask someone to get an AED

NB:

  • timely chest compressions are required
  • mouth to mouth improves survival -
  • rhythms may change from VF/VT to PEA/asystole
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13
Q

What protocol is used for cardiac arrest in hospital?

A
  • Recognise and call 2222
  • Start CPR and continue until defibrillator is retrieved

Shockable rhythms:

  • Give 1 shock ASAP - remove oxygen to prevent fire during defibrillation. NB: Witnessed monitored cardiac arrest due to VF/pVT: 3 stacked shocks
  • Each shock followed by 5 cycles (=2mins) of chest compressions
  • Airway adjuncts inserted ASAP (tracheal tube or SGA) with 100% oxygen - NB: CPR given at 10/min without pausing CPR (unless leakage occurs with SGA → 30:2)
  • Vasopressor: Give adrenaline after 3rd shock then repeat every 3-5mins
  • Antiarrhythmic: Give amiodarone 300mg IV/IO after 3rd shock then again 150mg after the 5th shock
  • Then restart algorithm at adrenaline again if rhythm still shockable

Non-shockable rhythms:

  • Vasopressor: Give adrenaline 1mg IV/IO ASAP then every 3-5mins
  • Airway adjuncts for oxygen delivery
  • Chest compressions 2 mins/5cycles
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14
Q

Describe post resuscitation care in cardiac arrest.

A
  • Monioring - ECG
  • Organ support
  • Correct electrolytes and acidosis
  • Transfer to ICU
  • Anoxic brain injury is a frequent complication - keep patient warm to reduce this
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15
Q

When should you terminate resuscitation?

A

Ethically challenging - no single factor determines this but rather clinical judgement and respect for human dignity.

In prehospital setting, resuscitation may be terminated if:

  • The patient had no return of spontaneous circulation (ROSC) before transport
  • No shock was administered
  • Emergency medical services did not witness the arrest.
  • Delayed initiation of CPR in unwitnessed arrest
  • Unsuccessful after 20min of ACLS
  • Conditions of pt compromise safety of care providers
  • Pt has “do not resuscitate” order
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16
Q

How common is cardiac arrest in terms of hospital admissions?

A

1.6 per 1000

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17
Q

What are the most common presenting rhythms in cardiac arrest?

A

Shockable (pulseless VT/VF) - 16.9%

Non-shockable (PEA/asystole) - 72.3%

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18
Q

What are the complications of cardiac arrest and its management?

A
  • Death - >85% out of hospital
  • Rib and sternal fractures
  • Anoxic brain injury
  • ischaemic liver injury
  • Renal acute tubular necrosis
  • Recurrent cardiac arrest
19
Q

List 4 causes fo hypoxic cardiac arrest.

A
  • pneumonia
  • pulmonary oedema
  • ards
  • asthma
  • asphyxia
20
Q

How do you manage hypoxic cardiac arrest?

A
  • secure airway
  • oxygenate with 100% oxygen initially
  • treat cause
21
Q

What is a cause of hypovolaemic cardiac arrest?

A

Usually haemorrhage i.e. trauma, GI loss, AAA rupture

22
Q

What is the management of hypovolaemic cardiac arrest?

A
  • secure airway and ventilate
  • restore intravascular volume
  • stop losses e.g. surgery, endoscopy
  • stop any hypotension (caused by anaphylaxis or sepsis can also cause cardiac arrest)
23
Q

What is the management of hyperkalaemic cardiac arrest?

A
  1. secure airway and ventilate
  2. calcium chloride – PROTECT HEART
  3. insulin/glucose – SHIFT K INTO CELLS
  4. sodium bicarbonate – SHIFT K INTO CELLS/CORRECT ACIDOSIS
24
Q

What are the causes of hyperkalaemic cardiac arrest?

A
  • renal failure
  • drugs
  • tissue breakdown
  • metabolic acidosis
  • endocrine disorders
25
Q

What are 3 signs of hyperkalaemia on this ECG?

A
  • flattened or absent P waves
  • tall (tented) T waves
  • widened QRS
  • VT
26
Q

What are the ECG changes in different electrolyte disturbances?

A

hypocalcaemia - QT prolongation

hypercalacemia - ST shortening

hypokalaemia - long QU interval, prominent U

hyperkalaemia - peaked T waves

hypomagnasaemia - tall T, depressed ST segment

hypermagnasaemia - prolonged PR, widened QRS

27
Q

What is classed as mild/mod/severe hypothermia?

A

Mild - 32-35

Mod - 28-32

Severe - <28

28
Q

What are the stages of hypothermia?

A

Stage I - conscious and shivering

Stage II - impaired consciousness without shivering

Stage III - unconscious

Stage IV - no breathing

Stage V - death due to irreversible hypothermia

29
Q

What is the management of hypothermic cardiac arrest?

A
  • “no one is dead until warm and dead”
  • secure airway and ventilate with warm humid oxygen
  • CPR
  • withhold adrenaline until above 30 degrees - then do a double interval between adrenaline doses
  • treat arrhythmias
30
Q

What measures are taken to reverse hypothermia?

A
  • cut away cold/wet clothes
  • full body insulation
  • chemical heat pack
  • warmed IV fluids/warmed O2
  • internal warming e.g. gastric and bladder lavage
  • extracorporeal warming in specialised centres
31
Q

Name 3 toxin causes of cardiac arrest and a key clinical feature in each.

A

Opioids - pinpoint pupils with resp arrest

Benzodiazepines - LOC and resp depression (flumazenil uncommonly used)

TCA - hypotension, seizures, arrhythmias (IV Na bicarb target 7.45-7.55, or IV MGSO4 if broad QRS)

32
Q

What are the causes of thrombotic cardiac arrest?

A

Coronary thrombosis

Pulmonary embolism

33
Q

What is the commonest cause of cardiac arrest?

A

coronary thrombosis

34
Q

How long should you continue CPR in PE cardiac arrest?

A

60-90min - good survival and outcomes

35
Q

What are 3 causes of tamponade?

A
  • penetrating trauma
  • cardiac surgery
  • PPM insertion
36
Q

How do you diagnose tamponade?

A

bedside echo

37
Q

What is the management of tamponade?

A
  • needle pericardiocentesis
  • resuscitative thoracotomy
38
Q

What are 3 clinical signs of tension pneumothorax?

A
  • unilateral expansion of chest
  • tracheal shift
  • subcut emphysema
39
Q

What are 3 causes of tension pneumothorax?

A

trauma

central line insertion

NIV

40
Q

What is the management of tension pneumothorax?

A
  1. needle decompression (thoracocentesis) - 2nd ICS in MCL
  2. chest drain is definitive management
41
Q

What is the management of asystole?

A

Adrenaline every 3-5mins and CPR

This is a non-shockable rhythm

Asystole has a poor prognosis so it is unlikely that resuscitation will be successful

42
Q

What is the fluid of choice for a bolus during cardiac arrest?

A

Crystalloid - e.g. 0.9% saline or Hartmanns should be used to give fluid bolus’.

Glucose would not remain in the intravascular volume and therefore so little to help the hypovolaemia.

43
Q

What is the ALS protocol in cardiac arrest after hypothermia?

A

In cases of hypothermia causing cardiac arrest, defibrillation is less effective and only 3 shocks should be administered before the patient is rewarmed to 30 degrees centigrade