cardiac and vascular emergencies Flashcards
ischemic heart disease (aka coronary artery disease) can be broken down into what two categories
- stable angina
- acute coronary syndrome
acute coronary syndrome can be broken down into what three categories
- STEMI
- NSTEMI
- unstable angina
clinical presentation
- pressure, heaviness, tightness, fullness, or squeezing in the center or left of the chest precipitated by exertion and relieved by rest
angina (pectoris)
the anginal equivalents: exertional dyspnea, nausea, diaphoresis, weakness, palpitations, syndrome are more commonly in what patient population
- elderly
- diabetic
diagnostic testing for angina
- 12-lead EKG
- stress testing
- coronary angiography
pharmacologic stress echocardiogram is performed using what drug
dobutamine
indications for pharmacologic stress echo
- unable to exercise
- inability to achieve target HR during exercise (beta-blocker)
technique of radionuclide myocardial perfusion imaging
- rest images obtained
- exercise or pharmacologic stress induced
- radioactive tracer administered under stress conditions
- exercise/stress images obtained
- perfusion defect will be seen in areas of hypoperfusion
treatment regimen for stable angina
- nitrates
-
beta blockers: first line for chronic angina
- CCB: no response to nitrates and beta blockers
-
antiplatelet medication
- asa
- clopidogrel (plavix)
management of low risk patients with normal EKG
- observation
- serial cardiac enzymes
- stress testing and CT coronary angiography, can assist CV risk stratification in ED
Variant Angina (prinzmetal angina, vasospastic angina) typically have what episodes of chest pain
- episodes of angina (5-15 min)
- usually at rest and often between midnight and early morning
what is diagnostic for Variant Angina (prinzmetal angina, vasospastic angina)
- coronary angiography
treatment of Variant Angina (prinzmetal angina, vasospastic angina)
- nitrates
- CCB
workup of chest pain in the ED includes
- EKG
- CXR
- pulse oximetry
- labs: CBC, CMP, D-dimer, lipids, BNP, cardiac enzymes (Troponing, CK-MB)
- echocardiogram
- angiography
initial management of STEMI
- MONA
- morphine
- oxygen
- nitroglycerin
- aspirin 325 mg, chewed
- beta blocker
- anticoagulation: unfractionated heparin
preferred mechanism for revascularization in STEMI
- PCI: Percutaneous coronary intervention
- if not available in 120 minutes -> fibrinolytics
what are the absolute contraindications to thrombolytics
- hx of hemorrhagic CVA
- ischemic CVA in last 3 months
- presence of a cerebral vascular malformation or intracranial malignancy
- suspected aortic dissection
- active bleeding
- significant closed-head or facial trauma within the preceeding 3 months
what is the gold standard for diagnosing CAD? what interventions can it do
coronary angiography
- interventions:
- angioplasty
- stenting
revascularization options
- PCI
- fibrinolytic therapy: tPA
- antiplatelet therapy: glycoprotein IIb/IIIa inhibitor
- CABG
define a NSTEMI
- non-occlusive thrombus
- ischemia with elevated cardiac enzymes
clinical presentation
- CP with increasing severity, frequency, duration
- occurs at rest
- not relieved with rest and/or nitroglycerin
unstable angina
inital managment of NSTEMI/unstable angina
- MONA
- morphine
- oxygen
- nitroglycerin
- asa 325 mg, chewed
- beta blocker
- anticoagulation: unfractionated heparin
- revascularization (PCI, if needed)
- no thrombolytics
ask about the use of what before giving nitroglycerin
- sildenafil
- vardenafil
- tadalafil
clinical presentation
- usually occurs soon after MI (first 2-3 days)
- transient
- +/- chest discomfort
- PE: pericardial rub
- echo: pericardial effusion
- per-infarction pericarditis (PIP)
treatment of per-infarction pericarditis (PIP)
- ASA + colchicine
- *avoid NSAIDS*
clinical presentation
- chest pain, tachypnea, dyspnea
- hypotension, JVD, muffled heart sounds, pulsus paradoxus
pericardial tamponade
how is acute mitral regurgitation diagnosed
- TTE: transthoracic echocardiogram
ischemia to papillary muscle post MI can cause
acute mitral regurgitation