Cardiac Flashcards

1
Q

What is the mechanism of Thiazide Diuretics?

A

Increases excretion of sodium and water by inhibiting reabsorption in the distal tubule.

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2
Q

What are the uses of Thiazide Diuretics?

A

Treats hypertension and edema.

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3
Q

What are the side effects of Thiazide Diuretics?

A

Hypokalemia, dehydration, hyperglycemia.

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4
Q

What is a key point to remember when using Thiazide Diuretics?

A

Monitor potassium levels.

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5
Q

What is the mechanism of High Ceiling Loop Diuretics?

A

Inhibits sodium and chloride reabsorption in the loop of Henle.

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6
Q

What are the uses of High Ceiling Loop Diuretics?

A

Treats pulmonary edema, hypertension, and heart failure.

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7
Q

What are the side effects of High Ceiling Loop Diuretics?

A

Hypokalemia, dehydration, ototoxicity.

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8
Q

What is a key point to remember when using High Ceiling Loop Diuretics?

A

Monitor for low potassium, kidney function, and hearing changes.

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9
Q

What is the mechanism of Potassium-Sparing Diuretics?

A

Antagonizes aldosterone receptors, leading to sodium excretion and potassium retention.

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10
Q

What are the uses of Potassium-Sparing Diuretics?

A

Often used in heart failure and hypertension.

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11
Q

What are the side effects of Potassium-Sparing Diuretics?

A

Hyperkalemia, gynecomastia.

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12
Q

What is a key point to remember when using Potassium-Sparing Diuretics?

A

Avoid potassium supplements.

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13
Q

What is the mechanism of Beta Blockers?

A

Blocks beta receptors, reducing heart rate and contractility.

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14
Q

What are the uses of Beta Blockers?

A

Hypertension, angina, heart failure.

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15
Q

What are the side effects of Beta Blockers?

A

Bradycardia, hypotension, fatigue.

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16
Q

What is a key point to remember when using Beta Blockers?

A

Do not stop abruptly; may worsen angina.

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17
Q

What is the mechanism of Calcium Channel Blockers?

A

Inhibits calcium ions in vascular smooth muscle and myocardium, leading to vasodilation.

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18
Q

What are the uses of Calcium Channel Blockers?

A

Hypertension, angina.

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19
Q

What are the side effects of Calcium Channel Blockers?

A

Edema, dizziness, hypotension.

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20
Q

What is a key point to remember when using Calcium Channel Blockers?

A

Monitor blood pressure regularly.

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21
Q

What is the mechanism of ACE Inhibitors?

A

Inhibits ACE, reducing angiotensin II, which lowers blood pressure.

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22
Q

What are the uses of ACE Inhibitors?

A

Hypertension, heart failure, diabetic nephropathy.

23
Q

What are the side effects of ACE Inhibitors?

A

Cough, hyperkalemia, angioedema.

24
Q

What is a key point to remember when using ACE Inhibitors?

A

Avoid in pregnancy; monitor potassium.

25
What is the mechanism of ARBs?
Blocks angiotensin II receptors, lowering blood pressure.
26
What are the uses of ARBs?
Hypertension, heart failure.
27
What are the side effects of ARBs?
Dizziness, hyperkalemia.
28
What is a key point to remember when using ARBs?
Often used if ACE inhibitors cause cough.
29
What is the mechanism of Cardiac Glycosides?
Increases myocardial contractility and decreases heart rate.
30
What are the uses of Cardiac Glycosides?
Heart failure, atrial fibrillation.
31
What are the side effects of Cardiac Glycosides?
Toxicity (nausea, vision changes), bradycardia.
32
What is a key point to remember when using Cardiac Glycosides?
Monitor digoxin levels and renal function.
33
What is the mechanism of Nitrates?
Causes vasodilation, reducing myocardial oxygen demand.
34
What are the uses of Nitrates?
Angina relief.
35
What are the side effects of Nitrates?
Headache, hypotension, dizziness.
36
What is a key point to remember when using Nitrates?
Do not take with phosphodiesterase inhibitors (e.g., sildenafil).
37
What is the mechanism of Anticoagulants?
Inhibits factors in the clotting cascade.
38
What are the uses of Anticoagulants?
Prevents clot formation in conditions like DVT, PE.
39
What are the side effects of Anticoagulants?
Bleeding, thrombocytopenia.
40
What is a key point to remember when using Anticoagulants?
Heparin requires monitoring of aPTT; Lovenox is often preferred for outpatient.
41
What is the mechanism of Vitamin K Antagonists?
Inhibits vitamin K-dependent clotting factors.
42
What are the uses of Vitamin K Antagonists?
Long-term prevention of DVT, PE, and stroke in AFib.
43
What are the side effects of Vitamin K Antagonists?
Bleeding, bruising.
44
What is a key point to remember when using Vitamin K Antagonists?
Monitor INR levels; vitamin K is the antidote.
45
What is the purpose of Antidotes like Vitamin K and Protamine Sulfate?
Vitamin K reverses Warfarin effects; Protamine Sulfate is an antidote for heparin overdose.
46
What is a key point to remember when using Antidotes?
Used only in cases of significant bleeding or toxicity.
47
What is the mechanism of Antiplatelets?
Inhibits platelet aggregation.
48
What are the uses of Antiplatelets?
Prevents arterial clots, stroke, MI.
49
What are the side effects of Antiplatelets?
Bleeding, GI upset.
50
What is a key point to remember when using Antiplatelets?
Monitor for signs of bleeding, especially with other anticoagulants.
51
What is the mechanism of Statins?
Inhibits cholesterol synthesis in the liver.
52
What are the uses of Statins?
Lowers LDL cholesterol, reduces cardiovascular risk.
53
What are the side effects of Statins?
Muscle pain, liver enzyme elevation.
54
What is a key point to remember when using Statins?
Monitor liver function; avoid grapefruit juice.