CARD 44- Pharm: Anticoagulant, Platelet Inhibitor and Thrombolytics Flashcards by Dominic Shuttleworth | Brainscape

Q

What is the MOA of Low molecular weight heparin (LMW)?
What drug is an example of it
What effect does it have on factor Xa? Thrombin?
What are its drawbacks? advantages?

A

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Q

Describe the MOA and PK for Fondaparinux

A

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Q

What are the GP IIb/IIIa Receptor Antagonists?

A

ATE GP

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Q

What are the steps of Hemostasis?

A

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Q

What inhibitor platelet aggregation drug does this describe?

Blocks ADP receptors on platelets

A

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Q

What is the MOA of Heparin?

A

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Q

What are the Pharmacogenomic Considerations: for Warfarin

A

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Q

What is the MOA for Warfarin?

A

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Q

What are the ADP Receptor Antagonists?

A

Clones Prepared to be ADePt

Tony the Tiger reversed

Ticagrelor is reversible

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Q

What inhibitor platelet aggregation drug does this describe?

Blocks formation of TxA2

A

Aspirin

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Q

What are the DDIs and ADRs for aspirin?

A

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Q

Describe the PKs and ADRs for GP IIb/IIIa Receptor Antagonists

A

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Q

How does aspirin affect Cox-1 vs Cox-2?

A

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Q

What are the ADRS for Warfarin?

Describe Warfarin reversal

A

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Q

What are the “substances”?

A

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Q

Where is heparin found?

What are the types of Heparin?

A

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Q

What are the PKs for Warfarin?

What do you need to monitor?

What is it used for?

A

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Q

What are the DDIs and ADRs for ADP Receptor Antagonists?

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Q

What are the ADRs of Direct thrombin inhibitors?

A

Q

What are the uses and PKs for Fibrinolytics/Thrombolytics?

A

Q

What is the MOA for GP IIb/IIIa Receptor Antagonists?

A

Q

Describe the MOA, PK, and ADRs for Rivaroxaban

A

Q

What are the 2 substances responsible for stimulating platelet aggregation?

A

Q

What is aspirin used for?

What are its PKs?

A

Q

What are the DDIs for Warfarin?

A

Q

What are PKs for ADP Receptor Antagonists?

A

Q

What is the MOA for Fibrinolytics/Thrombolytics?

A

Q

What are the Factor Xa Inhibitors?

What DDI do they all share?

A

Fondaparinux

Rivaroxaban

Fond of Rivers

Q

What inhibitor platelet aggregation drug does this describe?

Blocks the receptor used for platelet aggregation

A

Q

What is Ticagrelor?

A

A reversible ADP receptor antagonist

Q

What are these examples of?

A

Warfarin

Q

What are the Direct thrombin inhibitors and their PKs?

A

Dab Again

Q

What molecules do Antiplatelet agents inhibit?

A

Q

What are the DDIs and ADRs for Low molecular weight heparin (LMW)?

A

Q

What is the MOA of Unfractionated heparin (HMW)?

What effect does it have on factor Xa?

What are its drawbacks?

A

Q

What receptor do platelets use to attach to one another?

A

Q

What are the uses of Direct thrombin inhibitors?

What use is specific for Dabigatran?

A

Q

What are the Fibrinolytics/Thrombolytics?

A

ART PLASE

Q

What are the types of Anticoagulants and what are they used for?

A

Q

What are the Hemostatics?

What are they used for and what their MOAs?

A

Q

What is Streptokinase?

Describe its PKs and ADRs

A

Q

What do you use GP IIb/IIIa Receptor Antagonists for?

A

Patients with recent MI or stroke or PCI

Q

What is the MOA for ADP Receptor Antagonists?

A

Irreversibly inhibit ADP receptor on surface of platelets (necessary for platelet aggregation)

Q

What is the MOA for Aspirin?

A

Q

What are ADP Receptor Antagonists used for?

A