Carcinogenesis Flashcards
Clasificación o tipos de carcinógenos
- Chemicals
- Oncogenic viruses
- Radiation
De donde provienen las aflatoxinas que provocan carcinoma hepatocelular?
Derived from Aspergillus which can contaminate stored grains
Cuál es el mecanismo por el que el alcohol provoca carcinoma de páncreas?
Es derivado de la chronic pancreatitis
Cuál es el principal cancer causado por la exposición a asbesto?
Lung cancer (mesothelioma)
What is the most important carcinogen in cigarette smoke?
Polycyclic hydrocarbons
What carcinogen chemicals are related to occupational exposure and what type of cancer are derived from each one?
Vinyl chloride (to make PVC)—> angiosarcoma of liver
Nichel, chromium, beryllium, sylica —> lung carcinoma
Mention the high risk HPV subtypes
16, 18, 31, 33
What is the mechanism of ionizing radiation to developed cancer?
Generates hydroxyl free radicals