carboprost tromethamine (Hemabate)

Question 1

medication used for controlling POSTPARTUM HEMORRHAGE

Answer 1

carboprost tromethamine (Hemabate)

Question 2

suppresses bleeding primarily by causing intense uterine contractions & partly by causing vasoconstriction.

Answer 2

carboprost tromethamine (Hemabate)

Question 3

bleeding can generally be stopped in most cases with ONE single dose; IM, 250-mg. IF NEEDED, same dose can be repeated every 15-90 minutes BUT DO NOT EXCEED 2 GRAMS.

Answer 3

carboprost tromethamine (Hemabate)

Question 4

Adverse effects for carboprost tromethamine (Hemabate)

Answer 4

-GI reactions/GI upset
-vomiting + diarrhea occurs in up to 60% of patients
-nausea is also V common
-GI reactions can be reduced with PRETREATMENT
with antiemetic + antidiarrheal meds.
-fever is common
-causes vasoconstriction as well as constriction of the
bronchi
-may result in HYPERtension + impaired respirations

Question 5

Contraindications for carboprost tromethamine (Hemabate)

Answer 5

• acute pelvic inflammatory disease

- active disease of heart, lungs, kidneys, liver

Question 6

Precautions for carboprost tromethamine (Hemabate)

Answer 6

• Asthma
• HYPERtension
• Diabetes
• Uterine scarring