Carbonyl Chemistry Flashcards
1
Q
What makes the carbonyl susceptible to nucleophilic attack?
A
The dipole, with C being slightly positive
2
Q
Order acid anhydrides, carboxylic acids, esters, amides, acyl chlorides from most to least reactive
A
Acyl chlorides
Acid anhydrides
Esters and carboxylic acids
Amides
3
Q
What is a thioester?
A
RCOSCH3 R-(C=O)-S-CH3
Natural version of an acid anhydride, with the SCH3 as the leaving group in substitution
