Carbohydrate Metabolism-Pentose Phosphate Pathway Flashcards
1
Q
What is the committed step in Pentose Phosphate Pathway?
A
The committed step of Pentose Phosphate Pathway is the G6P DEHYDROGENASE
***G6P DEHYDROGENASE converts G6P to 6-PHOSPHOGLUCONOLACTONE
2
Q
What are the by-products of G6P Dehydrogenase and why is it so important?
A
The by-products of G6P Dehydrogenase is NADPH. This is a very important by-product because it is used by FA Synthase in FA synthesis.
***It is also used in Glucathione regeneration which is an antioxidant; helps DECREASE CONCENTRATIONS OF H202.
3
Q
Which type of cells have VERY HIGH pentose phosphate pathway activity and why?
A
Phagocytic cells because they are always transcribing mRNA codes for proteins to destroy pathogens!
