Carbohydrate Metabolism- Glycogenolysis

Question 1

How does the chain shortening of glycogenolysis occur?

Answer 1

Glycogenolysis chain shortening occurs through glycogen phosphorylase that cuts the alpha-1,4- glycosidic linkages. Debranching enzyme cuts the alpha-1,6- linkages and adds them to the glycogen alpha-1,4- linkage chain.

***glycogen phosphorylase KEEPS cutting them up into G-1-P!!!!!!!!!!

Question 2

Where does glycogenolysis occur?

Answer 2

The majority of glycogenolysis occurs in the cytoplasm.

**HOWEVER, there is a SMALL AMT that occurs in the LYSOSOMES.