Capillaries and lymph Flashcards
2 main body compartments
60% water and 40% solid
Subparts of the water make up in body
2/3 intracellular fluid
1/3 extracellular fluid
Parts of extracellular fluid
Interstitial fluid
Plasma
Interstitial fluid
Fluid between the cells (surrounding and within tissue)
Types of capillaries
Continuous
Fenestrated
Sinusoidal
Continuous capillary
Tightly joined epithelial cells that regulate selective molecular exchange
Leaky junctions at the cleft of the cells
Fenestrated capillaries
Contains pores that facilitate increased permeability for fluid and small molecules
Location of fenestrated capillaries
Intestinal wall and endocrine organs
Which capillaries have a continues basement membrane
Continuous and fenestrated
Sinusoidal capillary
Capillaries with large gaping spaces enabling passage of cells and large molecules
There is an increase in exchange across the membrane so decrease in regulation
2 primary pressures acting on water within capillaries (starling forces)
Hydrostatic pressure and oncotic pressure
Starling forces
Forces that drive the fluid exchange in capillaries
Determines net movement of H20
Hydrostatic pressure
Filters water out of the capillary into the interstitial space
Forces within hydrostatic pressure
Cap. hydro pressure pushes fluid out of capillary
Interstitial hydro pressure pushes fluid into the cap.
Oncotic pressure
Absorbs water from the interstitial space into capillary
What creates constant oncotic pressure in blood vessels
Albumin
How to determine if net efflux or influx of water
If the answer is negative then water moves into the capillary
If answer is positive water moves out
Lymphatic system functions
Return excess interstitial fluid to the venous circulation
Pick up fat absorbed and transfer to circulatory system
Filter for pathogens
Thoracic lymphatic duct location
Largest lymph vessel, located in posterior mediastinum and terminates in left brachiocephalic vein
Function of thoracic lymphatic duct
Collects lymph from all parts of the body except the right side of head, neck, thorax, and right upper limb
Right lymphatic duct
Terminates in the right brachiocephalic vein
Function of the right lymphatic duct
Collects lymph from right side of the head/neck, right thorax, and right upper limb
Lymph nodes
Where unfiltered lymph drains
Lymph node and immune response
Dendrite in node detects bacteria and presents antigen
B cells react and make antibodies