CAP Test 2019 Flashcards
What type of vision causes light to be focussed in front of the eye?
Myopia
Lens used to correct myopia
Concave )(
Symptoms of renal colic
Sudden onset Severe unilateral pain Loin to groin colicky Often assoc with haematuria
Symptoms of adenexal (ovarian) torsion
Severe intermittent colicky pain
N + V
Complications if ovarian torsion not surgically corrected
Necrotic (pyrexia)
First line investigation for newborn bilious vomit
Abdominal x-ray
Investigation for suspected pyloric stenosis
US - thickened pylorus
Baby who is constipated with projectile vomit. Well and eager to feed
Pyloric stenosis
Hypertensive that causes ankle oedema
Ca channel blocker (Amlodipine)
First line for paroxysmal AF
Betablocker (bisoprolol)
Diagnosis of delirium
Acute onset plus, inattention with fluctuating course
And one of:
Disorganised thinking
Altered level of consciousness
Minimum percentage blood loss in femur fracture
30%
Position for neonatal x-rays
supine
Appearance of surfactant deficiency in neonatal x–ray
Lung volume reduced
In what patient group are breast abscesses common
Lactating women
What is a galactocoele
Painless breast lump secondary to protein plus blocking the outlet of the mammary glands for milk
How do fibroadenomas tend to present?
Younger women
Mobile smooth breast lumps
Risk factors for NEC
Intrauterine growth restriction
Absent end diastolic flow at placenta
Prematurity
Hypoxic ischaemic insult
Management of infants at risk of NEC
Close monitoring
Breast milk as early as poss
Gradual increase in the total volume of enteral feed
What do Men B titres show?
Reaction to routine childhood vaccinations
What test should be done before LP in kids with meningiococcal septicaemia?
Clotting screen
What marker is raised in GCA?
ESR
What should be measure prior to lithium prescription?
Renal function
What hormone triggers ovulation?
LH
How long after LH surge is ovulation?
24 to 36 hours
Where is LH released from?
Anterior pituitary
What class of drug is metformin?
Biguanide
What hould be added if metformin not enough in T2DM?
Sulphonylurea (Glicazide)
When should sulphonylureas not be used?
Risks of hypo too hight
If sulphonylureas contraindicated what should be added to metformin in management of T2DM?
Thiazolidinedione (TZD) - e.g. proglitazone
Which medication for T2DM causes diarrhoea?
Metformin
What does 1:1000 mean in drug dosing?
1g in 1000ml
How does memantine work?
Blockade of NMDA-type glutamate receptors
What is memantine used in the treatment of?
Dementia
Well-defined hair loss with normal underlying skin. Likely diagnosis?
Alopecia areata
What are exclamation mark hairs seen in?
Alopecia areata
What is aqueous humour produced by?
Cilliary body
How is aqueous humour drained?
At the angle of the eye
Through trabecular meshwork
Into the canal of Schlemm’s
Management of bronchiolitis
Oxygen therapy + NG feeding
Distribution of seborrhoeic dermatitis
Eyebrows
Nasolabial folds
Scalp
Itchy vesicles on extensor surfaces
Dermatitis herpetiformis
Initial management of oesophagitis
PPI
Bird beak appearance
Achalasia
Management of Achalasia if young and fit
Heller’s cardiomyotomy
Management of Achalasia if not young and fit
Balloon oesophageal dilatation
Management of oesophageal stricture impairing feeding
Oesophageal balloon dilatation
Investigation for suspected PE in patient on chemo
CTPA
1st line investigation for suspected endometrial ca
US (for endometrial thickness) or pipelle biopsy
What can group B strep cause in preterm infants
Neonatal meningitis
What is the most common cause of encephalitis in neonates?
Herpes Simplex
How is Herpex simplex encephalitis in a neonate seen on imaging?
Inflammation of temporal lobr
Cause of CNS infection in neonates, elderly and immunocomprimised
Listeria monocytogenes
Food sources of listeria monocytogenes
Soft cheese
Unpasturised milk
Signs of L4 pathology
Absent knee reflex
Weakness in knee extension
Foot drop
First line short term post-partum contraception
COCP or POP
Investigation of suspected malaria
Thick/thin blood film
What is the first line investigation for suspected pneumoperitoneum?
Erect chest x-ray
What is the gold standard investigation for pneumoperitoneum?
CT
What is the antidote for paracetamol overdose?
Acetylcysteine
What information is needed to calculate an acetylcysteine dose?
Body weight
What time period in acetylcysteine most effective in?
Within 8 hours
What time period should activated charcoal be given in in paracetamol overdose/
Within 1 hour
When should acetylecysteine be used in paracetamol overdose?
Plasma-paracetamol conc on or above treatment line
presentation 8-24hrs after acute ovrdose of more thn 150mg/kg
Whta is the most appropriate first line management for a patient with urinary incontinence with large urinary volumes?
Reduce fluid intake
How is urge incontinence managed?
Bladder retraining
Antimuscarinics (e.g. oxybutinin, tolterodine)
B3 agonist (e.g. miraberon)
How is stress incontinence managed?
Pelvic floor exercise
B agonists
What causes urge incontinence?
Detrusor overactivity
What causes overflow incontinence/
Bladder outlet obstruction (e.g. prostate enlargement)
When is mirabegron useful in incontinence management?
Urge incontinence - if there is concern about anti-cholinergic side effects in frail elderly patients
Cause of haematuria associated with URTI?
IgA nephropathy
In which cardiac patients are NOACs not licensed for use/
Prosthetic heart valves
What type of infection is Trichomonas vaginalis?
A protozoal (single cell) parasite
What is the genetic abnormality in DiGeorge syndrome?
Deletion in Chromosome 21
How does DiGeorge syndrome present clinically?
Recurrent infections (problems in T-cell response)
Cardiac disease
Defects in palate and lip
What is chronic granulamtous disease?
Genetically caused immunodeficiency which usually presents in childhood with recurrent infection (including abscess and atypica infections)
Clinical features of open angle glaucoma
Raised IOP
Increased disc cupping
field defects
Insidious onset
What effect do parasympathetic nerves have on the bladder?
Excited the bladder while relaxing the urethral muscle (voiding)
What effect do sympathetic nerves have on the bladder?
Relaxes the detrusor while contracting urethral sphincter (not voiding)
Where do afferent stimuli from the destrusor go?
Brainstem
Where in the brain controls micturition?
Frontal cortex
What test is used to diagnose coeliac disease?
Tissue Transglutamase
What patient demographic does dermatomyositis present in?
Women
50-70 y/o
Clinical presentation of dermatomyositis
Gradual onset proximal muscle weakness
Purple rash on sun exposed areas
What effect does Vit D deficiency have on PTH levels?
PTH levels increase
What effect does Vit D deficiency have on calcium and phosphate levels?
Calcium and phosphate levels will be low
What effect does Vit D deficiency have on Alk Phos levels?
Alk Phos levels increase
Why do Alk Phos levels increase in Vit D deficiency?
Increased osteoblastic activity
What is leaden paralysis?
Feeling of heaviness in the legs
What are hypersomnia and leaden paralysis symptoms of?
Atypical depression
Name 4 complications of meningitis in children
SIADH
Hearing loss
Subdural effusion
Hydrocephalus
What is the most common cause of bacterial food poisoning in the UK?
Campylobacter
Which bacterial gastroenteritis can lead to haemolytic uraemi syndrome?
E.cli 0157
Why should antibiotics be avoided in treating E.coli 0157?
May precipitate onset of HUS
How does PTH increase calcium levels?
Directly decreases calcium reabsorption from the kidneys
Increases conversion of Vit D to 1,25 hydroxy vit D which increases calcium reabsorption in the gut
What effect do high serum calcium levels have on pTH?
Negative feedback on PTH secretion
Which anti-psychotic should be used in pregnancy/
Olanzapine
What drug should be used in treatment resistant schizophrenia?
Clozapine
Which anti-epileptic drug interacts with lithium?
Carbamazepine
What effect do NSAIDs have on lithium>
Decrease lithium excretion
Which test in marked out of 100 and is suitable for asessing an lder person who presents with new memory problems?
Adenbrookes
Which neurotransmitter is affected in withdrawal from sedative-hypnotic drugs?
GABA
Which neurotransmitter is responsible for symptoms in schizophrenia?
Dopamine
Which neurotransmitter is low in depressed patients?
5-hydroxytryptamine (serotonin)
What measures the degree to which individiuals differ from sample mean?
Standard deviation
How are autoimmune blistering disorders diagnosed?
Biopsy and immunofluorescence
Why does phenytoin reduce he efficacy of the COCP?
Induces liver enzymes
How should patients with GORDs airway be supported during general anaesthesia?
Intubation
How is pseudogout diagnosed?
Arthrocentesis - calcium pyrophosphate crystals change colour under polarizing filter with change of the polarization alignment
Drug given for patient in AF who is cardiovascularly stable
Amiodarone (rate control)
B blockers
Drug to give patient who is hypotensive with normal heart rate
Noradrenaline (central access)
Metaraminol (peripheral access)
How does epidymo-orchiditis present?
Unilateral
Acute onset of pain, swelling and tenderness