Cannabinoids

Question 1

Describe the dose/effects for cannabinoids.

Answer 1

Low-dose (3-4 mg): mild sedation, disinhibition, mild disorientation. High-dose (15 mg): tachy, postural hypotension, CNS depression, aniety, perceptual disturbances, psychotic symptoms

Question 2

How do cannabinoids work?

Answer 2

Psychoactive drug with central sympathomimetic anc antiemetics properties. Acts on central/peripheral nervous system (CB1) and immune cells (CB2). Augments dopamine release.

Question 3

What are the effects of cannabinoids?

Answer 3

CNS: ataxia, impaired judgement, CNS depression, coma in children. CVS: tachy, orthostatic hypotension, syncope. Psychiatric: agitation, hallucinations, acute psychosis, euphoria. Respiratory: pneumothorax, pneumomediastinum

Question 4

What can be a serious effect of cannabinoids in children?

Answer 4

Coma for up to 36 hours

Question 5

What are the effects of cannabinoids on children?

Answer 5

Rapid onset coma, hypotonia, abnormal movements, tachycardia and bradycardia lasting 24-36 hours