CANMAT depression

Question 1

Risk factors for depression:

Answer 1

Family history, history of depression, psychosocial adversity, high users of medical system, chronic medical conditions, other psychiatric conditions, times of hormonal changes, unexplained systems, chronic pain, fatigue, insomnia, anxiety, SUD

Question 2

symptom response on a scale

Answer 2

more or equal to 50% decrease in baseline score

Question 3

risk factors for chronic/recurrent depression

Answer 3

earlier age of onset, increased number of previous episode, severity of initial episode, disruptions of sleep-wake cycle, comorbid psychopathology, fam history, negative cognitions, high neuroticism, poor social support, stressful life events

Question 4

Try of MDD in children/ youth

Answer 4

1-CBT or internet based psychotherapy/ interpersonal therapy
2-fluoxetine
escitalopram, sertraline, citalopram
3-venlafaxine, TCA (not in children only ado)

Question 5

pedo, increase rx after

Answer 5

4 weeks

Question 6

perinatal dep 1st line

Answer 6

CBT (indiv/ group), IPT (indie, group)

Question 7

perinatal dep 2nd line

Answer 7

citalopram, escitalopram, sertraline

Question 8

highest risk antidepressants for preg

Answer 8

paroxetine, venlafaxine, fluoxetine

Question 9

Trx of mild-moderate PPD during breastfeeding, 1st line

Answer 9

CBT, IPT (individu/group)

Question 10

Trx of mild-moderate PPD during breastfeeding, 2nd line

Answer 10

citalopram, escitalopram, sertraline

Question 11

can women breastfeed with ECT?

Answer 11

yes

Question 12

Trx perimenopausal depression treatment 1st line

Answer 12

desvenlafaxine

CBT

Question 13

Trx perimenopausal depression treatment 2nd line

Answer 13

transdermal estradiol

citalopram, duloxetine, escitalopram, mirtazapine, seroquel xr, venlafaxine xr

Question 14

Late life depression treatment 1st line

Answer 14

Duloxetine, mirtazapine, nortriptiline

bupropion, citalopram, escitalopram, desvenlafaxine, duloxetine, sertraline, venlafaxine, vortioxetine

Question 15

Late life depression treatment 2nd line

Answer 15

Switch to nortriptiline

Question 16

1st line depression level 1

Answer 16

bupropion, citalopram, desvenlafaxine, duloxetine, fluoxetine, mianserin, milnacipran, mirtazapine, paroxetine, sertraline, venlafaxine, vortioxetine, escitalopram

Question 17

2nd line depression level 1

Answer 17

amitriptyline, clomirpramine and other TCAs, levomilnacipran, moclobemine, quetiapine, selegiline T/D, trazodone, vilazodone

Question 18

3rd line depression level 1

Answer 18

phenelzine, tranulcypromine, reboxetine

Question 19

with mixed fratures

Answer 19

lurasidone, ziprasidone

Question 20

with sleep disturbances:

Answer 20

agomelatine

mirtazapine, quetiapine, trazodone

Question 21

with somatic symptoms

Answer 21

duloxetine, bupropion (fatigue),

Question 22

lower risk of sexual s/e

Answer 22

agomelatine, bupropion, mirtazapine, vilazodone, vortioxetine

Question 23

worst for QTC

Answer 23

citalopram, escitalopram, quetiapine

Question 24

algorithme

Answer 24

x

Question 25

Adjuncts 1st line

Answer 25

abilify, seroque, risperda

Question 26

Adjuncts 2nd line

Answer 26

brexiprazole, bupropion, lithium, mirtazapine, modafinil, olanzapine

Question 27

Abilify

Answer 27

2-15

Question 28

Seroquel

Answer 28

150-300

Question 29

Risperdal

Answer 29

1-3

Question 30

bupropion

Answer 30

150-300

Question 31

citalopram

Answer 31

20-40

Question 32

fluoxetine

Answer 32

20-60

Question 33

mirtazapine

Answer 33

15-45

Question 34

sertraline

Answer 34

50-200

Question 35

venlafaxine

Answer 35

75-225

Question 36

vortioxetine

Answer 36

10-20

Question 37

escitalopram

Answer 37

10-20