Cancer Risk Models Flashcards
1
Q
What are the 4 family history-weighing breast cancer risk models?
A
Tyrer-Cuzick, BRCApro, CanRisk (formerly BOADICEA), Claus
2
Q
What are the limitations of Gail model?
A
Validated for women between 35 and 85
Not appropriate for women with pathogenic variant in BRCA1 or BRCA2 (and likely other genetic susceptibility)
Women with previous history of breast cancer
3
Q
What information can you put into the Gail model?
A
personal, medical, and reproductive history
breast cancer history among FDRs
4
Q
Who is the Gail model most appropriate for?
A
average risk women!
5
Q
What does CanRisk calculate?
A
risk of breast or ovarian cancer
