Cancer Meds Negative reactions Flashcards
Myocardial ischemia, myelosuppresion
5-FU (breast cancer, colon cancer, gastric and pancreatic cancer)
Reversible pneumonitis, hepatic fibrosis
Methotrexate
Neuropathy, SIADH
Vincristine (ALL, hodgkin lymphoma, neuroblastoma, non hodgkin lymphoma, rhabdomyosarcoma)
Interstitial fibrosis
Bleomycin (Blenoxane); head and neck cancers, hodgkin lymphoma, malignant pleural effusions, testicular cancer
Cardiomyopathy
Doxorubicin, trastuzumab ( breast cancer and others)
HUS, blue green urine
Bicalutamide (casodex) ( prostate cancer, metastatic)
Hemorrhagic cystitis, bladder cancer
Cyclophosphamide
Hand and foot blisters
Sunitinib (gi stromal tumor, pancreatic neuroendocrine tumor, renal cell carcinoma)
Neuropathy, bradycardia
Paclitaxel
Anal pruritis, HUS, flu, rash
Gemcitabine (Gemzar) (breast cancer,metastatic; non small cell lung cancer, metastatic; ovarian cancer, pancreatic cancer
Hot flashes, thromboemboli, endometrial cancer, increased calcium
Tamoxifen (Nolvadex); give citalopram(breast cancer)
Impotence, transient cancer flare, osteoporosis
GNRH agonists (lupron, zoladex)
Leukopenia, thrombocytopenia, myelosuppression
Hydroxyurea (Hydrea); CML, head and neck cancers, sickle cell anemia
Myelosuppression, hypotension, weakness, alopecia
Etoposide (etophophos); small cell lung cancer, testicular cancer
Nephrotoxic, ototoxic, neuropathy
Cisplatin (platinol); bladder, ovarian and testicular cancer