Cancer Meds Negative reactions Flashcards

1
Q

Myocardial ischemia, myelosuppresion

A

5-FU (breast cancer, colon cancer, gastric and pancreatic cancer)

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2
Q

Reversible pneumonitis, hepatic fibrosis

A

Methotrexate

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3
Q

Neuropathy, SIADH

A

Vincristine (ALL, hodgkin lymphoma, neuroblastoma, non hodgkin lymphoma, rhabdomyosarcoma)

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4
Q

Interstitial fibrosis

A

Bleomycin (Blenoxane); head and neck cancers, hodgkin lymphoma, malignant pleural effusions, testicular cancer

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5
Q

Cardiomyopathy

A

Doxorubicin, trastuzumab ( breast cancer and others)

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6
Q

HUS, blue green urine

A

Bicalutamide (casodex) ( prostate cancer, metastatic)

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7
Q

Hemorrhagic cystitis, bladder cancer

A

Cyclophosphamide

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8
Q

Hand and foot blisters

A

Sunitinib (gi stromal tumor, pancreatic neuroendocrine tumor, renal cell carcinoma)

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9
Q

Neuropathy, bradycardia

A

Paclitaxel

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10
Q

Anal pruritis, HUS, flu, rash

A

Gemcitabine (Gemzar) (breast cancer,metastatic; non small cell lung cancer, metastatic; ovarian cancer, pancreatic cancer

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11
Q

Hot flashes, thromboemboli, endometrial cancer, increased calcium

A

Tamoxifen (Nolvadex); give citalopram(breast cancer)

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12
Q

Impotence, transient cancer flare, osteoporosis

A

GNRH agonists (lupron, zoladex)

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13
Q

Leukopenia, thrombocytopenia, myelosuppression

A

Hydroxyurea (Hydrea); CML, head and neck cancers, sickle cell anemia

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14
Q

Myelosuppression, hypotension, weakness, alopecia

A

Etoposide (etophophos); small cell lung cancer, testicular cancer

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15
Q

Nephrotoxic, ototoxic, neuropathy

A

Cisplatin (platinol); bladder, ovarian and testicular cancer

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16
Q

Flu like symptoms, increased LFTs, arthralgias, hypo/hyperthyroidism

A

Interferon alpha (chronic heptatis b)

17
Q

Capillary leak syndrome, erythema

A

IL-2 (melanoma)

18
Q

Rash, vitiligo, thyroiditis, worsening of auto immune diseases, diarrhea

A

Interferon alpha