cancer genes Flashcards

1
Q

RB

A

retinoblastoma

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2
Q

p53

A

Li-Fraumeni syndrome (various tumors)

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3
Q

p16/ INK4A

A

Melanoma

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4
Q

APC

A

Familial adenomatous polyposis/ colon cancer

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5
Q

NF1, NF2

A

Neurofibromatosis 1 and 2

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6
Q

BRCA1, BRCA2

A

breast and ovarian tumors

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7
Q

MEN1, RET

A

Multiple endocrine neoplasia 1 and 2

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8
Q

MSH2, MLH1, MSH6

A

Hereditary nonpolyposis colon cancer

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9
Q

PTCH

A

Nevoid basal cell carcinoma syndrome

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10
Q

PTEN

A

Cowden syndrome (epithelial cancers)

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11
Q

LKB1=STK11

A

Peutz-Jegher syndrome (epithelial cancers)

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12
Q

VHL

A

renal cell carcinoomas

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