cancer genes Flashcards
1
Q
RB
A
retinoblastoma
2
Q
p53
A
Li-Fraumeni syndrome (various tumors)
3
Q
p16/ INK4A
A
Melanoma
4
Q
APC
A
Familial adenomatous polyposis/ colon cancer
5
Q
NF1, NF2
A
Neurofibromatosis 1 and 2
6
Q
BRCA1, BRCA2
A
breast and ovarian tumors
7
Q
MEN1, RET
A
Multiple endocrine neoplasia 1 and 2
8
Q
MSH2, MLH1, MSH6
A
Hereditary nonpolyposis colon cancer
9
Q
PTCH
A
Nevoid basal cell carcinoma syndrome
10
Q
PTEN
A
Cowden syndrome (epithelial cancers)
11
Q
LKB1=STK11
A
Peutz-Jegher syndrome (epithelial cancers)
12
Q
VHL
A
renal cell carcinoomas