Cancer Colorrectal Flashcards

1
Q

Factores de riesgo

A

Síndromes hereditarios
Sd. lynch
Poliposis adenomatosa familiar

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2
Q

Clínica

A

Síntomas en etapas avanzadas

Colon derecho: Anemizante (hemorragia oculta)
Colon izquierdo: cambio en el patrón defecatorio (hematoquesia)
Recto: proctorragia

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3
Q

Metástasis

A

Hígado y pulmón

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4
Q

Marcador tumoral

A

CEA (antígeno carcinoembrionario)

Seguimiento en px con quimio
Marcador disminuye
Mejor pronóstico

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5
Q

Mutaciones

A

KRAS (codon 12 o 13) peor pronóstico
BRAF (codon 600) asociado al consumo de tabaco
MSI se hace en Cancer colorectal

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6
Q

RT

A

Responde bien en cancer de recto

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7
Q

Metástasis pulmonar y/o hígado

A

Quimio
Folfox o capricho con o sin bevacizumab
Folfoxiri con o sin bevacizumab

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