Cancer: An Overview Flashcards
describ- ing a loss of differentiation and more primitive appearance
undifferentiated/anaplastic
Tumors are divided into two categories:
benign or malignant
tumors that are generally well differentiated and do not metastasize or invade surrounding normal tissue
Benign
are encapsulated and slow growing
benign tumors
Benign tumors may be noted by the suffix -
oma
often invade and destroy normal surrounding tissue and, if left untreated, can cause the death of the host.
Malignant tumors
A ____ differentiated malignant tumor cell will resemble the cell from which it originated.
well or moderately well
A ____ cell will have very few of the characteristics of the originating cell
poorly differentiated
an _____ cell will have no
characteristics of the original cell
undifferentiated
Tumors arising from mesenchymal cells are known as ____.
sarcomas
These cells include connective tissue such as cartilage and bone.
Sarcomas
____ are tumors that originate from the epithelium.
Carcinomas
These include all the tissues that cover a surface or line a cavity.
Carcinomas
Epithelial cells that are glandular are called ____.
adenocarcinoma
are the result of abnormal cellular proliferation
Tumors
occurs when a cell undergoes mitosis and divides into daughter cells.
Cellular differentiation
are the normal genes that play a part in controlling normal growth and differentiation.
Proto-oncogenes
These genes are the precursors of oncogenes (gene that regulates the development and growth of cancerous tissues.), or cancer genes.
Proto-oncogenes
____ are also called tumor-sup-pressor genes. These are the genes that tell cells to stop mul-tiplying.
Antioncogenes
is the study of the cause of disease.
Etiology
is the study of disease incidence.
Epidemiology
is a means of defining the tumor size and extension at the time of diagnosis and is important for many reasons.
Tumor staging
The ____ of a tumor provides information about its aggressive-
ness and is based on the degree of differentiation.
grade
were established so that cancer specialists can work together to review information about newly diagnosed tumors and devise effective treatment plans.
Tumor boards
Through the use of _____, the radioactive sources can be placed next to or directly into the tumor.
brachytherapy
During an interstitial implant, radioactive sources are placed
_____ into the tumor.
directly