cancer

Question 1

Basal cell nevus syndrome

Answer 1

Chom 9q(9,22)
AD
Begin: Childhoodc early adolesence
Characteristic general eatures are rontal bossing, a broad nasal root, and hypertelorism

Tumors on the eyelids,axillae,and necktend to be pedunculated and are often symmetric on the face.palmoplantar lesions ,whicharepresentin50%
small pits thatare pinpoint tos everal millimeters insizeand 1mmdeep

Continue throughout life.

Question 2

Merkel cell CA

Answer 2

White skin
Immunosuppressed
Polyoma virus -80% found in merkel
high recurrence, spreads in lymph node in 50% more of pxs.

Pe: cutaneoustosubcutaneouspapule,nodule,ortumor(0.5to5cm)
re d t o v i o l e t o r r e d d i s h - b r o w n , d o m e - s h a p e d , a n d u s u a l l y s o l i t a r y

Dermatopathology shows nodular or dif use patterns o aggregated, deeply blue staining, small
basaloid or lymphoma-like-looking cells that can also be arranged in sheets orming nests, cords,
and trabeculae.

Tx: Excision, mohs and sentinel node biopsy