Cancer Flashcards

1
Q

why can lung infections be a symptom of cancer

A

a tumour may block the movement of mucus/sputum - this stasis makes it more likely for infection

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2
Q

what is horners syndrome

A

where a pan coats tumour impinges on the sympathetic trunk and the lower brachial plexus

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3
Q

what are the symptoms of horners syndrome

A

partial ptosis
constricted pupil
wastage of small muscles in the hand

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4
Q

what is seen in vena cava obstruction

A

engorged neck/check veins

bloated face

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5
Q

why might the diaphragm be elevated in lung cancer

A

the tumour may impinge on the phrenic nerve

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6
Q

what are the 3 types of non-small cell cancer

A

squamous cell carcinoma, adenocarcinoma, large cell carcinoma

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7
Q

what type of lung cancer is most common in non smokers

A

non-small cell adenocarcinoma

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8
Q

what are the differences between small cell and Non small cell carcinomas

A

small cell metastasises faster, grows faster and is found more centrally in the lungs around the bronchi

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9
Q

what are the 3 types of lung cancer

A

small cell, non-small cell and rare tumours

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10
Q

where can lung cancer spread

A

regional lymph nodes, brain, lungs, adrenal glands, bone, pleura

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11
Q

what investigations are done with suspected lung cancer

A

CXR, staging CT, PET scan, biopsy

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12
Q

what does a PET scan look out for

A

increased glucose uptake anywhere in the body - this looks for mets

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13
Q

what is a staging CT

A

like a chest CXR but can also see some of the abdomen to look for mets to the liver and adrenal glands

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14
Q

what paraneoplastic effects can small cell cancer have

A
  • Cushing’s syndrome as they cans secrete ATCH

- SIADH as they can secrete ADH leading to low sodium

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15
Q

what paraneoplastic effects can non small cell cancer have

A

can give high calcium as they secrete parathyroid related peptide hormone which acts like PTH

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16
Q

why may you look at ALP levels in suspected lung cancer

A

as it metastasises to the lungs

small cell can cause bone break down due to parathyroid related peptide hormone

17
Q

what is the treatment for lung cancer

A

if there are no mets - surgically removal. this has a good prognosis
can have radiotherapy/chemotherapy for curative or palliative care