Cancer Flashcards
Podophyllum peltatum/hexandrum
(North America/Himalayas)
Etoposide/teniposide blocks G1 mitosis phase
Tx testicular cancer, lymphomas
Podophyllotoxin/resin binds micro tubules, stops mitosis metaphase
Tx condylomata acuminata
Colchicum autumnale
Colchicum/colchicine (Europe)
Disorganized spindle at mitosis
Tx tumors, gout
Catharanthus roseus
(Madagascar)
Binds protein tubulin, stops mitotic metaphase
Vincristine: Tx acute childhood leukemia, non-hodgkins
Vinblastine: Tx hodgkins
Taxis brevifolia
Pacific yew
Taxol=antimucrotubule & antimitotic
Tx metastatic ovarian cancer, breast cancer
Camptotheca acuminata
Camptothecin (China)
Inhibits nuclear DNA topoisomerase I enzyme
Nerium oleander
(Mediterranean)
Stimulates tumor necrosis factor
Viscum album
European mistletoe
Tx breast cancer, joint inflammation
Solanum esculenta
Lycopene (south America)
Antioxidant, reduces risk of prostate cancer
Brassica oleracea
Kale, broccoli, Brussels sprouts
Lowers risk
Linum usitatissumum
Lignans reduce risk
Glycine max
Soybeans
Isoflavones, genistein: weak estrogen stimulators that outcompete estrogens
Reduce risk for breast, uterine, prostate cancers
Coffea robusta
Coffee reduced prostate and breast cancer risk
Zingiber officinalis
Ginger in teriyaki sauce reduces carcinogens on grilled meat
