Cancer Flashcards
What is cancer?
Cancer is when abnormal cells divide in an uncontrolled way as a result of gene changes within a cell- mutation
primary- where it starts
secondary- spreads to other body parts
most start due to gene changes that happen over a persons lifetime
Risk
High energy intakes
-High energy intakes through the consumption of fat (highest energy intake- 1g gives 9kals of energy) can contribute to cancer as positive energy balance leads to increased adipose tissue and hence overweight
-more fat, more fat tissue, more fat cells, more likely of cells to become abnormal
-obesity increases the risk of breast cancer in post menopausal women- after menopause, oestrogen levels gradually increase by 50%- due to increased hormone levels
-breast cancer is sensitive to levels of oestrogen and after the menopause, the main oestrogen source is from body fat, more body fat present, the higher levels of oestrogen
Fat Intakes
-promote carcinogens- increase free radicals in the body, damage DNA, cause cancer
the type of fat and amount contributes:
-PUFA omega 6- act as promoters of cancer and increase the risk of tumours in the breast and colon
-high fat intake levels- lead to positive energy balance- results in overweight and obesity- promoters of cancer
Sodium/ salt
-no more than 6g per day
-causative cancer factor
-high osmotic activity- linked to gastritis (inflammation of the stomach) result in early damage to the mucosa- acts as gastric irritant, leads to degeneration of the acid secreting glands in stomach and increases the acid secreting bacteria- produce carcinogenic substance- nitrosamines
-mono sodium glutamate- linked to stomach cancer