cancer Flashcards
1
Q
factors affecting response to chemotherapy
A
-decreased drug uptake
-increased drug removal (p-glycoprotein)
-drug metabolism
-increased levels of targets
-increased DNA repairing
-an alternative metabolic pathway
-blood supply
-tumor stage, grade and spread
-health, age, and pre-existing medical conditions
-drug metabolism
2
Q
what are the common side effects of chemotherapy
A
-anemia
-neutropenia
-nausea and vomiting
can be minimized by: carefully dosing drugs, combination therapy
