Cancer

Question 0

p53

Answer 0

afal

Question 1

Tumor Suppressor Genes

Answer 1

suppresses cancer formation

Question 2

aflatoxin

Answer 2

secreted by a fungus; a known carcinogen, leading to liver cancer. Mutates p53 gene

Question 3

hepatitis B

Answer 3

produces a protein that has the ability to bind p53 and prevent it from interacting effectively with target cells.

Question 4

Sustained angiogenesis

Answer 4

ability of cancer cells to enhance their blood supply. Angiogenesis: ability to make blood vessels

Question 5

Warburg effect

Answer 5

high anaerobic glycolysis in a normal cell –cancer prefers glucose; rapidly metabolize it, so this is indicative of cancer.

Question 6

miRNA

Answer 6

may become (or behave as) oncogenes or tumor suppressors by affecting the balance between cell cycling and death

Question 7

germ-line mutation

Answer 7

mutation inherited from parents ( BRCA1, BRCA2, Rb gene, DNA repair genes)

Question 8

BRCA1 and BRCA2

Answer 8

genes responsible for breast cancer risk

Question 9

Rb gene

Answer 9

gene responsible for retinoblastoma