Calorimetry Flashcards

1
Q

All metabolic processes result in

A

Heat production

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2
Q

Rate of heat production reflects

A

Rate of energy expenditure

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3
Q

Basic unit of heat measurement

A

calorie

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4
Q

Direct Calorimetry

A

Measuring heat directly

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5
Q

Indirect Calorimetry

A

Calculates O2 consumption and CO2 produced to determine how much break down you are engaging in

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6
Q

To convert amount of O2 consumed into heat equivalents depends on

A

Type of nutrient

about 5kcal of energy is liberated for each L of oxygen consumed

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7
Q

If have VO2 of 2L of oxygen per minute

A

5 x 2 = 10 kcal/min for energy expenditure

If you worked out for 10 minutes at the level, would burn 100 calories

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8
Q

What is indirect calorimetry measuring

A

Volume of expired oxygen
Fraction of expired gases
And then from here you calculate VO2 and VCO2 and then can calculate RER (VCO2/VO2) and can figure out what you are burning

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9
Q

Fraction of expired oxygen

A

about 16%

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10
Q

What is RER for 50/50 of carbs and fat burning

A

0.85

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11
Q

MET

A

Metabolic Equivalent

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12
Q

One MET =

A

Resting VO2

About 3.5 ml/kg of body mass/min

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13
Q

Energy cost of exercise can be described based on

A

Multiples of resting VO2

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14
Q

VO2 for 10 MET exercise

A

3.5 x 10 = 35 mL/kg/min

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15
Q

Light exercise is how many MET

A

2.5 to 5 METS

4 is usually good for patients

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16
Q

Metabolic Rate

A

Rate at which the body uses energy

17
Q

Basal Metabolic Rate

A

More of a lab setting

18
Q

BMR influenced by

A
Inc in muscle mass 
Inc in body surface area (thermoregulation)
Dec in age
Inc body temp
Inc  stress
Inc diet induced thermogenesis
19
Q

Oxygen uptake ____ until ____

A

Oxygen uptake increases linearly until VO2 max is reached

20
Q

Trained versus untrained with oxygen uptake

A

Untrained will plateau at an earlier state (VO2 max is lower)

21
Q

Factors influencing VO2 max

A

CO

AVO2 Max

22
Q

What is happening at rest

A

almost 100% of ATP is produced by aerobic metabolism
Blood lactate is low because are producing but getting rid of it just as fast
VO2 = 0.25L/min

23
Q

Transition to Exercise (from sitting)

A

Your muscles require energy immediately - ATP PCr provides until VO2 can catch up (until ETC can get there)
Repesents oxygen deficit

24
Q

Oxygen deficit with training

A

Decreases

You can get to steady state VO2 faster

25
Order for sitting to exercise
PCr (Anaerobic) Glycolysis (Anaerobic) ETC - VO2 catches up (Aerobic)
26
After you stop exercising what happens?
EPOC - Excess Post Exercise Oxygen Consumption You grow the deficit the more intense the exercise you start with is EPOC can happen for up to an hour or more
27
Why is metabolism still elevated after exercise
You are trying to reform stores of fuel and resynthesize and get all back to normal Fast portion - 1 to 3 minutes Slow portion - more than 30 minutes (elevated hormones and body temp)
28
If you inc rate of glyclosis more than ETC can handle
Pyruvate will get converted to lactic acid --> LDH important in this Fast twitch muscle fibers favor this lactic acid formation
29
Onset of Blood Lactate Accumulation
4mmol/L
30
Contributing factors to lactate in blood
Low muscle oxygen Accelerated glycolysis Recruitment of fast twitch fibers Reduced rate of lactate removal
31
Lactate Threshold - Untrained
50-60%
32
Lactate Threshold - Trained
70-90% | Will be at higher intensity before start to form lactate
33
Removal of lactate during exercise
Up to 40% produced in muscle is metabolized elsewhere Heart (70%) Type 1 fibers Liver - to produce glucose 6 phosphate (20%)
34
Removal of Lactate following exercise
If do nothing - takes longer to get rid of lactate | Light exercise - reduces this time
35
When you reach the lactate threshold what is happening to ventilation
It is increasing | Inc lactate --> inc acidity of blood --> more bicarb --> more CO2 --> hyperventilate
36
Ventilatory Threshold
When ventilation exceeds oxygen uptake
37
Thresholds represent
Point where your production has exceeded removal and this leads to increase in ventilation