Caldwell Pharm Flashcards

1
Q

Which 2 drugs have level 1 evidence for use in community acquired pneumonias in a non-ICU patient?

A

1) Respiratory Fluoroquinolones (Gemi, Moxi, and Levofloxacin) and 2) Beta-lactam + macrolide

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2
Q

Which drugs have level 1 evidence for use in community acquired pneumonia in an ICU patient?

A

Beta-lactams and respiratory fluoroquinolones

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3
Q

For an ICU patient with CAP what should be used instead of penicillins if there is an allergy? What about a non-ICU pt?

A

1) For ICU pt: fluoroquinolones and aztreonam and 2) fluoroquinolons

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4
Q

What are the 4 options for Tx of P. aeruginosa CAP?

A

1) Beta-lactam and Cipro/levofloxacin 2) Beta-lactam and tobramycin 3) Gentamicin and Azithromycin or 4) Gentamicin and Respiratory fluoroquinolone

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5
Q

What are 2 drugs for Tx of acute sinusitis? Which for M. catarrhalis?

A

1) Amoxicllin and TMP-SMX, M. catarrhalis is resistant to penicillins, so just TMP-SMX

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6
Q

Which 5 drugs can be used for Tx of chronic sinusitis?

A

1) Clindamycin 2) Cefazolin/metronidazole 3) Cefuroxime/metronidazole 4) Clarithromycin 5) Fluoroquinolones

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7
Q

Which intramuscular and oral agents can be used against streptococcal sore throat? What if penicillin allergy?

A

Intramuscular = Penicillin G Benzathine; Oral = Penicillin V; If allergic then erythromycin

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8
Q

Which 3 agents can be used for COPD exacerbations?

A

1) TMP-SMX 2) Doxy and 3) Azithromycin and Clarithromycin

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9
Q

Which 3 agents are used for highly penicillin-resistant pneumococcal infections?

A

1) Doxycycline 2) Clindamycin and 3) Levofloxacin

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10
Q

2 antibiotics for Legionella:

A

Fluroquinolone and Azithromycin (Carty/Chen say Erythromycin)

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11
Q

What are 3 agents that can be used for nosocomial pneumonia and MRSA?

A

Linezolid, Tigecycline, and Vancomycin

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12
Q

A healthy patient with S. pneumoniae should be Tx’d with?

A

Macrolide, again Carty says ampicillin

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13
Q

An outpatient w/ comorbidities and has S. pneumo should be Tx’d with:

A

Respiratory fluoroquinolone OR Beta-lactam + Macrolide

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14
Q

What general class of drug is used in CAP patients over 60?

A

Cephalosporins (2nd gen Loracarbef and Cefuroxime; 3rd gen Cefpodoxime and Ceftriaxone)

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