Calcium and Phosphate Flashcards
Name some food sources of Calcium
Dairy products
Green leafy vegetables
Salmon
Almonds
What are the functions of Calcium?
Building strong bones Blood clotting Nerve signal transmittance Contraction and relaxation of skeletal muscles Releasing hormones Keeping the heartbeat normal
What things regulate calcium levels?
Parathyroid hormone
Vitamin D
Calcitonin
They act on bones, kidneys, and GI tract to regulate Ca levels
What are the normal levels of calcium in the blood?
Total plasma calcium = 8.5 - 10.2 mg/dl
Diffusable = 4-5 mg/dl
Nondiffusable = 3-4 mg/dl
When is calcium increased?
Lung cancer Breast cancer Hyperparathyroidism Some medicines like thiazide diuretics Vitamin D intoxication, excessive dietary calcium
When is calcium decreased?
Hypoparathyroidism Vitamin D deficiency Malnutrition Malabsorption Decreased renal function
What are the sources of phosphate?
Meat and milk
What are the functions of phosphate?
Makes hydroxyapatite (Ca+2/PO4-3 salts)
Component of phospholipids, nucleotides, ATP, NADPH, etc.
As a buffer
Nerve signaling
What happens in hyperphosphatemia?
Phosphate combine with calcium and deposits in soft tissues like muscles
What are the causes of hyperphosphatemia?
Kidney problems
Dysfunction of their calcium regulation