CADASIL Flashcards
1
Q
CADASIL (Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy)
A
is a progressive, hereditary form of multi-infarct dementia.
The prevalence is about 2 per 100 000.
Onset is usually at a young age (mean: 35-40). The initial presentation is primarily with neurological features of stroke (1/3 of cases) or migraine (1/3 of cases). Psychiatric manifestations are the initial presentation in 15% of cases. Mood disorders and subcortical dementia are the most frequent form of psychiatric presentation.
