CAD Flashcards
Define CAD
Narrowing or blockage of coronary arteries
Risk factors for CAD unique to women
- Smaller coronaries, less developed collateral circulation
- Elevated inflamm state with loss of estrogen
- Lower baseline HDL
- Vague symptoms are normal
What is the main component in athero plaques?
LDL
How does DM contribute to CAD development?
Lowers HDL
Raises TGs and LDL
What is the most important diagnostic tool in CAD?
History
Medical management of CAD?
- BP, DM control, lifestyle changes
- Platelet inhibition
- NTG
Treatment of STEMI
- PCI (time is muscle!)
- Oxygen
- ASA 325 mg chewed
- NTG sublingual
- Morphine
- Heparin
- B blocker
Difference between STEMI and NSTEMI?
- STEMI = full thickness infarct
- NSTEMI = partial thickness infarct
What is prinzmetal angina?
- Coronary artery spasm
- Generally in clean coronaries in younger women
- Occurs in early AM
What causes prinzmetal angina?
Cold, stress, cocaine, smoking, vasoconstricting meds
What are complications of MI?
- Cardiogenic shock
- Heart failure
- Dressler’s syndrome
- Arrhythmias
What is cardiogenic shock?
- Large LV infarct leads to significant decrease in contractility
- Results in very low BP with inadequate supply of oxygen rich blood to body
What is Dressler’s syndrome?
- Fever, pleuritis, pericarditis
- Caused by autoimmune reaction to damaged heart muscle, can occur weeks or months after MI
Why are ACEI/ARBs used post-MI?
Shown to minimize LV dilation post-MI resulting in lower rates of HF and improved survival