CAC Flashcards
where does the CAC occur and what does it do
matrix, oxidizes the acetate in acetyl-CoA (2 carbon atoms converted to 2 CO2), final stage in the aerobic catabolism of CHOs, FA, AAs
what does it start and end with
oxaloacetate (OAA)
what type of pathway is the CAC
amphibolic (catabolic and anabolic)
what is made and lost in the reaction?
3 NADH, 1 FADH2, 1 GTP made
2 carbons lost as CO2
how does the cycle start?
acetyl-CoA condenses with oxaloacetate to make citrate
which steps are E capture steps
2, 4, 5, 6, 7, 9
what makes the citrate synthase reaction exergonic
hydrolysis of thioester
enzyme names
sadds dfd
which steps release NADH
isocitrate, alpha ketoglutarate, malate
which step release FADH2
succinate
which step releases GTP
succinyl-CoA
what is a synthetase
there is a nucleoside triphosphate involved
what regenerates GDP for the succinyl-CoA synthetase reaction
NDK
reactions of the citric acid cycle
20) condensation, cleavage of a thioester
13) isomerization (tertiary alcohol to secondary)
14) oxidative decarboxylation
15) oxidative decarboxylation, formation of a thioester
16) SLP
17) oxidation in complex II
18) hydration
19) oxidation
citric acid cycle is low when ATP is high, ADP is low, NAD+ is low
