Ca Channel Blockers

Question 1

Amlodipine

Answer 1

Norvasc
Dihyrdopyridines (DHPs) "Vascular Selective"

Question 2

Isradipine

Answer 2

Dynacirc
Dihyrdopyridines (DHPs) "Vascular Selective"

Question 3

Nisoldipine

Answer 3

Sular
Dihyrdopyridines (DHPs) "Vascular Selective"

Question 4

Nifedipine

Answer 4

Adalat / Procardia XL

Dihyrdopyridines (DHPs) “Vascular Selective”

Question 5

Feldopine

Answer 5

Plendil
Dihyrdopyridines (DHPs) "Vascular Selective"

Question 6

Nicardipine SR

Answer 6

Cardene SR

Dihyrdopyridines (DHPs) “Vascular Selective”

Question 7

Clevidipene

Answer 7

Cleviprex
Dihyrdopyridines (DHPs) "Vascular Selective"

Question 8

Diltiazem

Answer 8

Cardizem / Cartia / Dilcor / Tiazac

non-Dihyrdopyridines (non-DHPs) “Cardio Selective”

Question 9

Verapamil

Answer 9

Calan / Isoptin / Verelan / Covera

non-Dihyrdopyridines (non-DHPs) “Cardio Selective”

Question 10

DHP MOA

Answer 10

access the closed (inactive) Ca channel and stabilize it making the recovery process longer - mainly act on the vasculature (60-70% of closed channels are located in the vasculature)
“Vascular-Selective”

Question 11

non-DHP MOA

Answer 11

bind to open (active) channels, thus inactivating (closing) them and thus slowing down recovery - most open channels are found in the heart
“Cardio-Selective”