C5. The chemical basis of drug action 2 Flashcards
1
Q
what is a heterocyclic system?
A
-Rings that contain carbon atoms and other non-carbon atoms
-Non-carbon atoms are called heteroatoms (e.g. N, O and/or S)
2
Q
naming heterocyclic systems?
A
ONE NOTE
3
Q
Sulphur containing functional groups
A
ONE NOTE
4
Q
What does histamine do?
A
-Histamine stimulates the secretion of acid by the parietal cells
-Interacts with H2-receptors in the parietal cells
5
Q
Acidity and basicity in organic molecules?
A
ONE NOTE
6
Q
Impact of hybridisation on basicity?
A
ONE NOTE
7
Q
What was the first H2 receptor antagonist?
A
Cimetidine
STRUCTURE ON ONE NOTE
8
Q
Different H2 antagonists?
A
ONE NOTE
