C3&4 Hemodynamics and Doppler Flashcards
what are the 2 primary functions of the venous sys?
Return blood from capillaries to the heart
Act as a reservoir to maintain homeostasis
what % of blood is in veins?
80%
what is needed for blood to flow?
pressure or energy gradient (flow from high press to low)
when does blood lose press after it leaves the heart?
as it flows through high resistance vessels
what is the press at the level of the venules and capillaries?
15mmHg
whats hydrostatic press?
and how is it measured?
the weight of a column of blood or gravitational pressure, measured from the heart to a point of press
whats the primary factor in determining intravascular pressure? and how does this fact effect venous return?
hydrostatic press
impedes venous return
whats the hydrostatic pressure in a supine and standing position?
supine: 15mmHg because all body parts on the same level as the RA
standing: 110mmHg at ankles because gravity resists blood flow from the legs to the heart
(veins in leg dilate and blood pools)
whats the press at the RA?
0mmHg
which part of the body is pressure highest?
lower part
if you raise your arms above your head, what happens to hydrostatic press? and what type of value will it have
it lowers and becomes negative (because hydrostatic pressure is relative to the RA)
what causes hypotension and what does hypotension cause?
standing in one position for too long
you will faint
whats the hydrostatic press when your walking?
25mmHg
what are the mechanisms for venous return?
cardiac function respiration muscle contraction press gradient valves compliance
what type of pressure is responsible for the expand/contract on veins?
the intramural/intraluminal and interstitial pressure
what does compliance permit?
large increase in venous flow without significant increase in venous pressure
how does higher volumes and pressures effect compliance?
they decrease it
which have more compliance, veins or arteries?
veins
arteries have greater elasticity
whats transmural press and does it effect the shaped of the vein?
difference between intraluminal (inner) and interstitial (outer) pressures
yes, determines the cross sectional shape of the vein
whats intraluminal pressure (ILP)?
press within the vein (will increase will higher blood volume)
higher ILP = rounder vein
how are intraluminal and transmural press related?
directly
whats interstitial pressure (ISP)?
press outside of the vein
higher ISP = collapsed vein
describe the effects of high vs los transmural press
high: vein wall will become circular and distend
low: vein wall collapses and is elliptical shaped
how does valsalva maneuver effect the venous system? and flow?
it increases the press in both the upper and lower extremity veins
flow should stop or diminish in upper and lower body (flat waveform)
NO REVERSAL
what creates dynamic pressure?
contraction of heart
4 parts of venous wave
- atrial systole
- systolic wave
- atrial diastole
- diastolic wave
when are the two periods of increased venous flow during the cardiac cycle?
ventricular systole When AV (MV and TV) valves open
describe what happens to press and volume in the atria during ventricular systole
volume increases
press decreases
this lowers venous pressure because theres increased flow into the RA
does respiration have a greater effect on the upper or lower extremities?
lower
because upper is closer to heart (its more pulsatile)
does respiration have the same effect on venous flow when standing?
no, it has less
does expiration increase of decrease venous flow?
expiration increases venous flow
how does muscle contraction effect venous press?
it decreases it
where does flow most often occur when the muscles are relaxed?
in perforators from the superficial to deep veins
whats the venous heart?
calf muscle
which calf muscle are the most efficient of the pumps?
gastroc and soleus muscles
how much venous blood is ejected during 1 contraction?
40-60% of the veins volume (generates 200mmHg)
what is ambulatory venous hypertension and what causes it?
what does it cause?
abnormally high venous press when standing, caused by dysfunctional valves
Cause PRIMARY varicose veins and edema
does muscles contraction help blood return to the heart with ambulatory venous hypertension?
no, it expels blood in all different directions
which vessel is a common site for an UE valve?
jugular vein
where is the venous valve sinus?
what is its size compared to the vein?
what pathology is comply found here?
the are between the valve leaflet and the intimal wall
wider than the vein
thrombosis due to stagnent flow
are valves more commonly found in superficial or deep veins?
superficial
which vessel has the greatest # of valves
GSV (then LSV and calf veins)… # lower as you move up the leg