C Structure Flashcards
naked or envelope
naked
capsid has icosahedral symmetry
composed of VP1, VP2, VP3 and VP4 (viral protein). VP123 form surface of capsid, there is 180 subunits. primary structure of VP123 differs but all form a beta sheet structure call a beta barrel jely roll. it is wedge shaped. one beta sheet forms one wall. a 2nd formed a 2nd wall and third the floor. this shape facilitates interaxns btwn subunit forming a rigid subunit. inside capsid are 60 copies of VP4, they are non covalently attached
genome is inside
+ive strand RNA does not have cap. covalently attached to 5’ end is a protein called VPg. 3’ end has a eukaryotic like poly-a-tail. at 5; and 3’ end are untranslated terminal region