C. Renale. Flashcards
What are the 3 types of corynebacterium renale that can cause infections?
C.renale.
C. cystitidis.
C.pilosum.
What are the most pathogenic of the 3 corynebacterium renale that can cause infections?
C renale and C cystiditidis are very pathogenic.
C pilosum is less pathogenic.
What animals are mainly affected by C. renale?
Female cattle.
Why are the diseases caused by C. renale considered to be ascending diseases?
As the infections start from the bladder and ascend to affect the kidneys.
Are bull likely to be affected by C.renale infections?
They can be carriers, but females are more likely to be affected.
Are C.renale Gram - or Gram + bacteria?
Gram positive.
What morphology do C.renale bacteria have?
They are rod shaped.
What are the 2 main virulence factors on C.renale?
They have pili and urease which allows them to produce ammonia.
How C.renale transmitted between cattle?
They are sexually transmitted or are transmitted in a urine splash.
What animals are mainly infected by C. cystitidis?
Cattle.
What are the 4 main symptoms in cattle that are infected with C. renale and C. cystiditis?
Haemorrhagic cystitis.
Ulceration of the bladder.
Uretitis.
Pyelonephritis.
What is a common sign of C. renale and C. cystiditis infections?
Blood mixed with urine.
What are the 2 main symptoms in cattle that are infected with C. pilosum?
Mild cystitis.
Pyelonephritis in rare cases.
Is C. pilosum likely to cause disease in cattle?
No.
What are 3 common clinical signs of C. renale infections?
Blood filled urine, fever and anorexia.
What is a very common presentation of cattle that have a C.renale infection?
The animal often has an arched back as its kidneys are infected.
C. pilosum and C. cystitidis are most likely to cause disease in what animals?
Sheep and goats.
How do C. pilosum and C. cystitidis affect sheep and goats?
They cause preputial ulcerative dermatitis as the bacteria are normally found in the prepuce.
What is a pre-disposing factor to C. pilosum and C. cystitidis in sheep and goats?
A high protein diet as high urea excretion leads to increased amounts of ammonia.
How should we feed sheep with C. pilosum and C. cystitidis infrections?
Reduce the amount of dietary proteins.
What kind of sheep and goats are more at risk from C. pilosum and C. cystitidis infrections?
Male goats and sheep.
How does the increased amount of ammonia in C. pilosum and C. cystitidis infrections affect a goat or sheep?
They cause inflammation and ulceration to the skin of the prepuce.
What is the most important thing to do when treating C. pilosum and C. cystitidis infections?
Reduce the amount of protein in the diet.
Can we use antibiotics to treat C. pilosum and C. cystitidis infections?
Yes.
What shape are corynebacterium?
Club shaped.
Which corynebacterium is a major human pathogen?
C. diptheriae.
C. pseudotuberculosis causes what condition in sheep and goats?
Caseous lymphadenitis.
C. pseudotuberculosis causes what conditions in horses?
External and internal abscesses.
Ulcerative lymphangitis.
What is the major virulence factor of C. pseudotuberculosis?
Phospholipase D.
What are the symptoms of caseous lymphadenitis?
Abscesses in the skin and lymph nodes.
What antibiotics can be used to treat caseous lymphadenitis?
Penicillin and ampicillin.
What is the vaccine that used to treat caseous lymphadenitis?
A phospholipase D based vaccine.
What bacteria causes pigeon fever in horses?
Corynebacterium.
What 3 corynebacterium are bovine pathogens?
C. renale.
C. pilosum.
C. cystiditis.
What are the 3 symptoms of corynebacterium infections in cattle?
Urinary tract infections.
Cystitisis.
Pyelonephritis.
