C. Renale. Flashcards

1
Q

What are the 3 types of corynebacterium renale that can cause infections?

A

C.renale.

C. cystitidis.

C.pilosum.

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2
Q

What are the most pathogenic of the 3 corynebacterium renale that can cause infections?

A

C renale and C cystiditidis are very pathogenic.

C pilosum is less pathogenic.

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3
Q

What animals are mainly affected by C. renale?

A

Female cattle.

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4
Q

Why are the diseases caused by C. renale considered to be ascending diseases?

A

As the infections start from the bladder and ascend to affect the kidneys.

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5
Q

Are bull likely to be affected by C.renale infections?

A

They can be carriers, but females are more likely to be affected.

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6
Q

Are C.renale Gram - or Gram + bacteria?

A

Gram positive.

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7
Q

What morphology do C.renale bacteria have?

A

They are rod shaped.

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8
Q

What are the 2 main virulence factors on C.renale?

A

They have pili and urease which allows them to produce ammonia.

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9
Q

How C.renale transmitted between cattle?

A

They are sexually transmitted or are transmitted in a urine splash.

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10
Q

What animals are mainly infected by C. cystitidis?

A

Cattle.

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11
Q

What are the 4 main symptoms in cattle that are infected with C. renale and C. cystiditis?

A

Haemorrhagic cystitis.

Ulceration of the bladder.

Uretitis.

Pyelonephritis.

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12
Q

What is a common sign of C. renale and C. cystiditis infections?

A

Blood mixed with urine.

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13
Q

What are the 2 main symptoms in cattle that are infected with C. pilosum?

A

Mild cystitis.

Pyelonephritis in rare cases.

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14
Q

Is C. pilosum likely to cause disease in cattle?

A

No.

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15
Q

What are 3 common clinical signs of C. renale infections?

A

Blood filled urine, fever and anorexia.

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16
Q

What is a very common presentation of cattle that have a C.renale infection?

A

The animal often has an arched back as its kidneys are infected.

17
Q

C. pilosum and C. cystitidis are most likely to cause disease in what animals?

A

Sheep and goats.

18
Q

How do C. pilosum and C. cystitidis affect sheep and goats?

A

They cause preputial ulcerative dermatitis as the bacteria are normally found in the prepuce.

19
Q

What is a pre-disposing factor to C. pilosum and C. cystitidis in sheep and goats?

A

A high protein diet as high urea excretion leads to increased amounts of ammonia.

20
Q

How should we feed sheep with C. pilosum and C. cystitidis infrections?

A

Reduce the amount of dietary proteins.

21
Q

What kind of sheep and goats are more at risk from C. pilosum and C. cystitidis infrections?

A

Male goats and sheep.

22
Q

How does the increased amount of ammonia in C. pilosum and C. cystitidis infrections affect a goat or sheep?

A

They cause inflammation and ulceration to the skin of the prepuce.

23
Q

What is the most important thing to do when treating C. pilosum and C. cystitidis infections?

A

Reduce the amount of protein in the diet.

24
Q

Can we use antibiotics to treat C. pilosum and C. cystitidis infections?

A

Yes.

25
Q

What shape are corynebacterium?

A

Club shaped.

26
Q

Which corynebacterium is a major human pathogen?

A

C. diptheriae.

27
Q

C. pseudotuberculosis causes what condition in sheep and goats?

A

Caseous lymphadenitis.

28
Q

C. pseudotuberculosis causes what conditions in horses?

A

External and internal abscesses.

Ulcerative lymphangitis.

29
Q

What is the major virulence factor of C. pseudotuberculosis?

A

Phospholipase D.

30
Q

What are the symptoms of caseous lymphadenitis?

A

Abscesses in the skin and lymph nodes.

31
Q

What antibiotics can be used to treat caseous lymphadenitis?

A

Penicillin and ampicillin.

32
Q

What is the vaccine that used to treat caseous lymphadenitis?

A

A phospholipase D based vaccine.

33
Q

What bacteria causes pigeon fever in horses?

A

Corynebacterium.

34
Q

What 3 corynebacterium are bovine pathogens?

A

C. renale.

C. pilosum.

C. cystiditis.

35
Q

What are the 3 symptoms of corynebacterium infections in cattle?

A

Urinary tract infections.

Cystitisis.

Pyelonephritis.