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Bacteriology. 10. Gram Positive Bacteria. Corynebacterium. > C. Pseudotuberculosis. > Flashcards

C. Pseudotuberculosis. Flashcards

1
Q

What disease is caused by C.Pseudotuberculosis in sheep and goats?

A

Caseous lymphadenitis.

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2
Q

What disease is caused by C.Pseudotuberculosis in cattle and horses?

A

Ulcerative lymphangitis.

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3
Q

What are the symptoms of ulcerative lymphangitis?

A

Internal and external abscesses.

These abscesses resemble those found in cases of TB.

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4
Q

Can C.Pseudotuberculosis affect humans?

A

Yes.

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5
Q

Are C.Pseudotuberculosis intracellular bacteria?

A

They are facultative intracellular bacteria meaning they can live outside a cell, but prefer to infect cells.

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6
Q

Does the body find it easy to phagocytose C.Pseudotuberculosis bacteria?

A

No, as they have a lipid coat on their outer layer which protects them from phagocytosis.

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7
Q

What is the exotoxin released by C.Pseudotuberculosis bacteria?

A

Phospholipase D.

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8
Q

What animals are affected by the caseous lymphadenitis that is caused by C.Pseudotuberculosis bacteria?

A

Sheep and goats.

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9
Q

Is caseous lymphadenitis an infectious disease?

A

Yes.

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10
Q

What are the major symptoms of caseous lymphadenitis?

A

Abscesses in the skin, lymph nodes and internal organs.

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11
Q

How does caseous lymphadenitis affect the sheep or goat that it affects?

A

Animals will undergo weight loss and produce less wool/milk.

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12
Q

What disease is often referred to as thin ewe syndrome?

A

Caseous lymphadenitis.

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13
Q

What colour will the abscesses be in cases of caseous lymphadenitis?

A

They are pale green in the early stages.

They then harden and become darker in the later stages.

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14
Q

Where are the abscesses caused by caseous lymphadenitis found on the sheep or goat?

A

They can be internal or external.

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15
Q

How do we remove the abscesses caused by caseous lymphadenitis?

A

Surgically.

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16
Q

What areas of the body are affected by the external lymph nodes associated with caseous lymphadenitis?

A

The skin and peripheral lymph nodes.

17
Q

What 5 areas of the body are affected by the internal lymph nodes associated with caseous lymphadenitis?

A

The lungs.

The liver.

The kidneys.

The spleen.

The internal lymph nodes.

18
Q

What are the characteristics of the puss that are produced in the abscesses caused by caseous lymphadenitis?

A

The abscesses are pale green in the early stages.

The abscess becomes darker and harder/cheesy as it ages.

19
Q

Is weight loss common in cases of caseous lymphadenitis?

A

Yes.

20
Q

What is the best way to diagnose caseous lymphadenitis?

A

Smear or culture.

21
Q

Are antibiotics effective in cases of caseous lymphadenitis?

A

No, as it is difficult for the penicillin etc to get through the abcess.

22
Q

What is the best way to treat animals with cases of caseous lymphadenitis?

A

Via surgery.

23
Q

C.tuberculosis causes ulcerative lymphangitis in what animals?

A

Cattle and horses.

24
Q

What are the common symptoms of ulcerative lymphangitis in cattle and horses?

A

External and internal abscesses.

25
Q

When is it very difficult to diagnose ulcerative lymphangitis in cattle and horses?

A

If only internal abscesses are present.

26
Q

In ulcerative lymphangitis where are the external abscesses usually found?

A

On the hind legs or in the pectoral regions.

27
Q

What is ulcerative lymphangitis is characterised by?

A

Inflammation of the lymphatic vessels and abscesses on the legs.

28
Q

What is characteristic about the abscesses in ulcerative lymphangitis?

A

They release thick, green puss.

29
Q

Where are the external abscesses associated with ulcerative lymphangitis found on the body?

A

In the pectoral region or on the hindlimb.

30
Q

What is characteristic about the external abscesses caused by ulcerative lymphangitis?

A

They have a thick capsule and are filled with yellowy, green puss.

31
Q

What are the internal abscesses caused by ulcerative lymphangitis characterised by?

A

Weight loss, fever, depression or colic.

32
Q

What is the most likely organ to be affected the internal abscesses caused by ulcerative lymphangitis?

A

The liver.

33
Q

What would we look for when we culture C.Pseudotuberculosis?

A

We stain it to look for the club shaped/Chinese letter shaped rods.

34
Q

What is characteristic about C.Pseudotuberculosis when it grows on blood agar?

A

It forms very small colonies on blood agar.

35
Q

Can we use PCR and ELISA to test for C.Pseudotuberculosis?

A

Yes.

36
Q

How can we treat C.Pseudotuberculosis infections?

A

We can use antibiotics to treat the abscesses, but they must be strong enough to penetrate the abscess.

37
Q

Why are antibiotics not effective at treating the abscesses caused by C.Pseudotuberculosis infections?

A

As the abscesses have a thick capsule.

38
Q

What is the best way to treat the abscesses caused by C.Pseudotuberculosis infections?

A

It is best to surgically drain the external abscesses.

39
Q

Can we vaccinate against C.Pseudotuberculosis bacteria?

A

Yes, but the use of these vaccines varies from country to country.

Bacteriology. 10. Gram Positive Bacteria. Corynebacterium. (3 decks)

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