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Farmacologia > BZ > Flashcards

BZ Flashcards

1
Q

PRINCIPALMENTE HIPNOTICAS >24HS

A

VM PROLONGADA
NITRAZEPAM
FLURAZEPAM

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2
Q

PRINCIPALMENTE HIPNOTICAS 24HS

A

INTERMEDIA

FLUNITRAZEM
LOPRAZOLAM

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3
Q

PRINCIPALMENTE HIPNOTICAS <6HS

A

CORTA

MIDAZOLAM
QUAZEPAM

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4
Q

PRINCIPALMENTE ANTICONVULSIVANTES

A

CLONAZEPAM (RIVOTRIL)
- VO, GOTAS, SL
- MYOCLONUS INFANTIL

DIAZEPAM
- EV, VO, INTRATECAL
- ESTADO MAL EPILEPTICO

LORAZEPAM (TRAPAX)
- EV, SL, VO
- ESTADO MAL EPILEPTICO

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5
Q

RECEPTOR
BZ1
BZ2

A

BZ1 - HIPNOTICO, SEDANTE

BZ2 - MIEDO, ANSIEDAD

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6
Q

AGOSNISTAS SELECTIVOS DE BZ1

A

EFECTO HIPNOSEDANTE

  • ZOLPIDEM
  • ZOPICLONA
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7
Q

AGONISTA INVERSOS

A

INVIERTE EFECTOS NARCOTICOS DEL ETANOL

  • SARMAZENIL
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8
Q

ANTAGONISTAS DE BZ

A

FLUMAZENIL
- CREA BRONCOASPIRACION, MUY MIORELAJANTE

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9
Q

ALPRAZOLAM

A

BZ ATIPICA
ANTIDEPRESIVA

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10
Q

MIDAZOLAM

A

+++ HIPNOTICA
ACCION RAPIDA
EFECTO ANESTESICOS (+FENTANILO) EN ANESTESIA GENERAL

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11
Q

FLUMAZENIL

A

BLOQUEA RECEPTORES DE BZ, RECEPTOR GABA OPERA SOLAMENTE CON GABA

  • EN TTO DE INTOXICACIONES POR BZ Y DEPRESORES DEL SNC
  • EN RECUPERACION DE ANESTESIA GENERAL
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12
Q

TIEMPO DE USO DE BZ COMO ANSIOLITICO

A

PERIODOS CORTOS PARA EVITAR LA TOLERANCIA

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13
Q

ACCION OREXIGENA

A

INCREMENTA EL APETITO
INCREMENTA PESO

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14
Q

ACCION MIORELAJANTE

A

HIPOTONIA SIN AFECTAR LA LOCOMOCION NORMAL
EA: RONCAR, DISARTRIA

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15
Q

ACCION ANTICONVULSIVANTE

A

CLONAZEPAM - TTO CRONICO DE EPILEPSIA

DIAZEPAM - PARA ESTADO MAL EPILEPTICO (EV)

EN NINOS SE USA LA VIA RECTAL

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16
Q

ACCION ANESTESICA

A

MIDAZOLAM
BZ DE VIDA CORTA
- GENERAL AMNESIA ANTEROGRADA
- INDUCTOR PARA ANESTESIA O MANIOBRAS ORTOPEDICAS

17
Q

EA DE BZ

A

SON DOSIS-DEPENDIENTES
AUMENTAN CON LA EDAD
ATURDIMIENTO
ATAXIA
CONFUSION

TERATOGENICA SI USO EN 1RE TRIMESTRE = PALADAR ENDIDO

AFECTA MAS A NINOS Y ANCIANOS VIRGENES

18
Q

CONTRAINDICACIONES

A

NO EN LACTANCIA
NO EN 1RE TRIMESTRE

19
Q

FARMACOCINETICA
- METABOLISMO
- PASE DE BARRERAS
- LM
- SOLUBILIDAD

A

LIPOSOLUBLES, BUENA ABSORCION POR VO

METABOLISMO HEPATICO
- FASE 1: OXIDACION MITOCONDRIAL
- FASE 2: GLUCURONOCONJUGACION

ATRAVIESAN PLACENTA

EXCRETA POR LM

20
Q

BZ CON MENOS PASOS HEPATICOS

A

LORAZEPAM
SOLO FASE 1 = MENOS PESO PARA HIGADO

21
Q

INDICACIONES

A

ANSIEDAD
ABSTINENCIA ALCOHOLICA
CONTRACTUA MUSCULAR, HERNIAS
CONVULSIONES
INSOMNIO

22
Q

INTERACCIONES

A

ASOCIACION PELIGROSA CON ALCOHOL

Farmacologia (5 decks)

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