Bv Lec 4 Flashcards

1
Q

What is amblyopia

A

Visual neuro-developmental condition caused by persistent abnormal visual input in early years of life

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2
Q

What are the 3 requirements to clinically diagnose amblyopia

A

Presence of amblyogenic factors in the early critical period for visual development

Reduced BCVA after amblyogenic factor is removed

Absence of other pathologies of eye or visual pathways

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3
Q

What is the optical treatment (1st treatment) for amblyopia

A

Full time wear of glasses or CL
-cycloplegic refraction correcting full anisometropic difference, all myopia/astigmatism, full cyclo if hyperopic and esoT

-min 12wks full time before starting additional Tx

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4
Q

What is the additional therapies (step 2 treatment) for amblyopia

A

Patching

Atropine penalisation

Bangerter filters (blur over good eye)

Others/efficacy not confirmed

  • vision therapy
  • binocular TX/videogames, VR systems
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5
Q

What is the post treatment (step 3 Tx) for amblyopia

A

Follow ups every 6-8wks for at least 2 more visits

Restart active therapy if VA decreases

Maintain full time wear of glasses or CL

Keep refractive correction up to date and fully correct any anisometropia (6-12monthly cyclo if <12 or hyperopic)

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6
Q

What are the clinical types of amblyopia

A

1) unilateral or bilateral
2) amblyogenic factors (strab/refractive/form deprivation)
3) combined mechanism amblyopia

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7
Q

Visual consequences of amblyopia that is routinely assessed in clinic?

A

BCVA reduced in one or BE

Fovea crowding/contour interaction

Fixation unstable and poor motor fusion

Unbalanced interlocutors suppression

Reduced stereoacuity

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8
Q

Prevalences of 3 categories of amblyopia

A

Unilateral strabismic & or anisometropic 1-4%

Bilateral refractive 0.1-0.4%

Unilateral or bilateral form deprivation 0.01%

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9
Q

Prevalence of amblyopia is
4x higher in?
6x higher in?

A

4x - infants born premature or small for gestational age OR first degree relative with amblyopia

6x children with neuro developmental delays

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10
Q

How to diagnose amblyopia practically

A

Use crowded VA test

Check pupils and eye health

Check visual deficit matches amblyogenic factor

Confirm vision not getting better on its own

Check it child has >1 diagnosis

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11
Q

Why do we bother to treat unilateral amblyopia

A

Backup eye

Career opportunities

Binocular functions (Bv only improves as side benefit and not always)

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12
Q

What to check in follow up for optical Tx done every 4-6wks

A

History - compliance and visual symptoms

Monocular and binocular BCVA

Stereopsis and suppression

Cover test and vergence if Phoria

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13
Q

When to add additional treatments during optical treatment phase

A

VA improving = continue optical Tx

VA stabilising over 6wks with good compliance
= no additional if <1 line BUT if 2 lines then START

VA not improving = check compliance or amblyopia

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14
Q

What’s goal of additional therapies

A

To improve vision in the amblyopia eye by penalising the better seeing eye

Additional as still has to wear correction

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15
Q

Starting dose for patching

A

Mild/moderate amblyopia (VA better than 6/36): min 2hrs/day

Severe (VA worse than 6/36): 6hrs/day

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16
Q

8 Advice for parents for patching

A

1) MUST CONTINUE FULL TIME GLASSES EVEN WHEN PATCHED
2) Method- correct eye patch, no peeking, parent monitor
3) Hours - best continuously
4) Schedule - school/home, AM/PM
5) Visual activities - sit down, visually engaging
6) Reward systems
7) Warnings as child visually impaired
8) Warning 2 - non amblyopic siblings

17
Q

How to prescribe atropine penalisation initially

A

Atropine 1% in non amblyopic eye

Dosage 1 drop daily/2nd day/weekends depend on iris

Warn parents for anticholinergic/Side effects

18
Q

How to follow up atropine penalisation

A

Monthly

  • compliance: dilated, in correct eye
  • VA in fellow eye with pinhole & full cyclo rx
  • Va in amblyopic with habitual specs
  • Cover Test but stereopsis poor
19
Q

Effectiveness and ease of compliance between patching and atropine

A

Patching improves faster in first 3 months but both same outcome at 6 month-3 lines if 3-6yo

Patching takes multiple hrs/day but atropine 1min

20
Q

Physical side effects and social stigma of atropine vs patching

A
Patching = irritation with stick on patch
Atropine = light sensitivity, ocular irritation, facial flush

Stigma high for patching so avoid school and low for atropine as can’t tell dilated

21
Q

What is amblyopia regression

A

reemergence of amblyopia due to residual neuroplasticity so gradual loss in Va or stereopsis gain after stopping active Tx

22
Q

Who has a higher risk for regression of amblyopia

A

1) Stopping Tx young age
2) px that improved more in Tx
3) not tapering high does patching
4) not wearing up to date correction