Buzzwords Flashcards

1
Q

blunted affect

A

schizophrenia

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2
Q

3rd person auditory hallucinations

A

schizophrenia

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3
Q

mesocortical dopamine hypoactivity

A

negative and cognitive symptoms in schizophrenia

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4
Q

subcortical dopamine hyperactivity

A

psychosis

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5
Q

mesolimbic Da blockade

A

depression

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6
Q

mesolimbic Da agonism

A

psychosis

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7
Q

clozapine SE

A

agranulocytosis, cardiomyocitis, a lot of weight gain

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8
Q

which atypical anti-psychotic causes the most weight gain

A

olanzapine

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9
Q

dopamine pathway in the brain concerned with prolactin release

A

tuberoinfundibular

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10
Q

dopamine pathway in the brain for extra pyramidal motor movements

A

nigrostriatal

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11
Q

dopamine pathway in the brain for motivation and reward

A

subcortical and mesocortical (sometimes known as mesolimbic system)

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12
Q

dopamine pathway in the brain dysregulated in schizophrenia

A

mesolimbic system

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13
Q

avoid TCAs in ….

A

cardiac problems or patients with suicidal intent

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14
Q

eosinophilic inclusions

A

Lewy bodies (LBD and PD)

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15
Q

interactions with tyramine containing foods, ephidrine, nasal decongestants, TCAs, pethidine

A

MAOI risk of hypertensive crisis (treat with phentolamine infusion)

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16
Q

48 and 72 h after last drink

A

delirium tremens

17
Q

within 48 h of last drink

A

alcohol withdrawal seizures

18
Q

what is flight of ideas and when is it seen

A

quickly moving from one topic to another but there is a link, in bipolar during manic phase

19
Q

what is knight’s move thinking and when is it seen

A

quickly moving from one topic to another with no link, in bipolar during manic phase

20
Q

Beck’s triad

A

-ve feelings about self, world and future

21
Q

NMDA antagonist SE

A

produce psychotic symptoms

22
Q

learning disabilities IQ

A

borderline 70-80 ish, mild 50-69, moderate 35-49, severe 20-34, profound <20

23
Q

brain region involved in normal response to threa

A

amygdala

24
Q

brain region that dampen downs amygdala response to threat

A

pre-frontal cortex

25
Q

EPSE tx

A

procyclidine

26
Q

thought blocking and what is it associated with

A

abrupt and complete interruption of stream, strongly associated with schizophrenia

27
Q

what is poverty of thought

A

patient reports lack/absence of thoughts

28
Q

what is pressure of thought, and what is it associated with

A

varied ideas in abundance (characteristic of mania but can also be seen in schizophrenia)

29
Q

reduced frontal lobe volume (and grey matter), enlarged lateral ventricles, reduced grey matter in the temporal cortex

A

brain changes in schizophrenia

30
Q

limbic system functions

A

M2OVE - motivation, memory, olfaction, visceral afferents and emotion