Buzzwords Flashcards
blunted affect
schizophrenia
3rd person auditory hallucinations
schizophrenia
mesocortical dopamine hypoactivity
negative and cognitive symptoms in schizophrenia
subcortical dopamine hyperactivity
psychosis
mesolimbic Da blockade
depression
mesolimbic Da agonism
psychosis
clozapine SE
agranulocytosis, cardiomyocitis, a lot of weight gain
which atypical anti-psychotic causes the most weight gain
olanzapine
dopamine pathway in the brain concerned with prolactin release
tuberoinfundibular
dopamine pathway in the brain for extra pyramidal motor movements
nigrostriatal
dopamine pathway in the brain for motivation and reward
subcortical and mesocortical (sometimes known as mesolimbic system)
dopamine pathway in the brain dysregulated in schizophrenia
mesolimbic system
avoid TCAs in ….
cardiac problems or patients with suicidal intent
eosinophilic inclusions
Lewy bodies (LBD and PD)
interactions with tyramine containing foods, ephidrine, nasal decongestants, TCAs, pethidine
MAOI risk of hypertensive crisis (treat with phentolamine infusion)
48 and 72 h after last drink
delirium tremens
within 48 h of last drink
alcohol withdrawal seizures
what is flight of ideas and when is it seen
quickly moving from one topic to another but there is a link, in bipolar during manic phase
what is knight’s move thinking and when is it seen
quickly moving from one topic to another with no link, in bipolar during manic phase
Beck’s triad
-ve feelings about self, world and future
NMDA antagonist SE
produce psychotic symptoms
learning disabilities IQ
borderline 70-80 ish, mild 50-69, moderate 35-49, severe 20-34, profound <20
brain region involved in normal response to threa
amygdala
brain region that dampen downs amygdala response to threat
pre-frontal cortex
EPSE tx
procyclidine
thought blocking and what is it associated with
abrupt and complete interruption of stream, strongly associated with schizophrenia
what is poverty of thought
patient reports lack/absence of thoughts
what is pressure of thought, and what is it associated with
varied ideas in abundance (characteristic of mania but can also be seen in schizophrenia)
reduced frontal lobe volume (and grey matter), enlarged lateral ventricles, reduced grey matter in the temporal cortex
brain changes in schizophrenia
limbic system functions
M2OVE - motivation, memory, olfaction, visceral afferents and emotion
