buzzlightyear Flashcards
Superantigens
Subclass of pyrogenic exotosin, directly stim CD4 T cells
Viral infection
No phagocytes present!
Cytopathic inflammation
Viruses only
Naked virus genome
Must be icosahedral, naked can not be helical,
PFU
Plaque forming unit – amount in sample
+ssRNA strategy
Translate first, infectious by itself
-ssRNA strategy
Transcribe first, have RNApol in capsid, not infectious
Main cause of influenza variation
Segmented genome, antigenic shift
Pandemic criteria
Novelty, virulent, R-factor (person transmission)
Trivalent vaccine vs. flumist
Flumist is only for young, healthy people, no one at risk
3 types of herpesviruses
Alpha(neuro), gamma(lympho), beta (not alpha/gamma)
ICP47
Viral protein to block MHCI presentation in HSV-1
Corneal transplant
HSV-1
Neonatal herpes
HSV-2