Busty Flashcards

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1
Q

Exposed-uninfected

A

HIV resistant, only some are ccr5 neg-homozygous

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2
Q

Rapid progressors

A

HIV into AIDS within 3 years

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3
Q

Long term non-progressors

A

HIV for 20+years without AIDS

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4
Q

Elite controllers

A

HIV so low can barely be detected, <50copies/mL

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5
Q

Vif protein

A

Viral infectivity protein, required for infection

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6
Q

Vpu protein

A

Viral protein unknown function – for virus release

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7
Q

Non-permissive cells

A

Have anti-vpu and APOBEC3g

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8
Q

APOBEC3G

A

Anti-vif protein

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9
Q

Permissive cells

A

Lack anti-vpu and lack APOBEC3G, can be infected by viruses that also lack vif and vpu

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10
Q

2 routes of entry for neurotropic viruses

A

Hematogenous and neural

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11
Q

CNS abscesses

A

Bacterial only!

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12
Q

Kernig Sign

A

Resistance when try to flex hip and extend knee, pt flat

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13
Q

Brudzinski Sign

A

Pt flat, try to flex neck, knees legs flex reflexively

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14
Q

Confusion, hydrophobia

A

Rabies

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15
Q

Centripetal and centrifugal viral spread

A

Rabies

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16
Q

Rabies Rx

A

Depends on inoculating animal, vaccine and Ig

17
Q

Scrapie

A

Sheep spongiform encephalopathies

18
Q

Insomnia

A

CJD

19
Q

Startle Myoclonus

A

CJD

20
Q

M/M129

A

Higher risk for vCJD, instead of valine

21
Q

Cortical blindness

A

CJD

22
Q

Young people spongiform

A

vCJD, old is regular CJD